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Fibrinogen gamma chain Antibody

  • Catalog number
    bs-6895R
  • Product name
    Fibrinogen gamma chain Antibody
  • Size
    0.1ml
  • Short name
    Anti-Fibrinogen gamma chain
  • Long name
    Fibrinogen gamma chain Antibody
  • Also known as
    Fibrinogen gamma chain Antibody
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Fibrinogen gamma chain
  • Specificity
    This is a highly specific antibody against Fibrinogen gamma chain.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    171-190/453
  • Subcellular location
    Secreted, Helical
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen gamma chain
  • Gene ID number
    2266
  • Swiss Prot
    P02679
  • Tested Applications
    WB, IHC-P, IF(IHC-P)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    Fibrinogen gamma chain; FGG; PRO2061
  • Gene target
    Fibrinogen gamma chain
    • Gene info
    Locus Specific Databases:LOVD EAHAD Coagulation Factor Variant DatabaseLRG_585
  • Gene symbol
    FGG
  • isotype filter
    • Immunoglobulin G IgG
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies