- Catalog numberbs-6895R
- Product nameFibrinogen gamma chain Antibody
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-Fibrinogen gamma chain
- Long nameFibrinogen gamma chain Antibody
- Also known asFibrinogen gamma chain Antibody
- CategoryPrimary Antibodies
- ConjugationUnconjugated
- HostRabbit (Oryctolagus cuniculus)
- Target AntigenFibrinogen gamma chain
- SpecificityThis is a highly specific antibody against Fibrinogen gamma chain.
- Modification sNone
- Modification site sUnmodified antibody
- ClonalityPolyclonal antibody
- Clone numberPolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range171-190/453
- Subcellular locationSecreted, Helical
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen gamma chain
- Gene ID number2266
- Swiss ProtP02679
- Tested ApplicationsWB, IHC-P, IF(IHC-P)
- Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
- Cross reactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the target antigenTogether with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
- Synonym namesFibrinogen gamma chain; FGG; PRO2061
- Gene targetFibrinogen gamma chain
- Identity:HGNC:3694
- Gene:FGG
- Long gene name:fibrinogen gamma chain
- Synonyms gene name:fibrinogen, gamma polypeptide
- Discovery year:2001-06-22
- Entrez gene record:2266
- RefSeq identity:NM_021870
- Classification:Fibrinogen C domain containing, Receptor ligands
- VEGA ID:OTTHUMG00000150329
- Gene symbolFGG
- isotype filter
- Immunoglobulin G IgG
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:LOVD EAHAD Coagulation Factor Variant DatabaseLRG_585