- Catalog numberbs-10417R
- Product nameFactor VIIIa light chain Antibody
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-Factor VIIIa light chain
- Long nameFactor VIIIa light chain Antibody
- Also known asFactor VIIIa light chain Antibody
- CategoryPrimary Antibodies
- ConjugationUnconjugated
- HostRabbit (Oryctolagus cuniculus)
- Target AntigenFactor VIIIa light chain
- SpecificityThis is a highly specific antibody against Factor VIIIa light chain.
- Modification sNone
- Modification site sUnmodified antibody
- ClonalityPolyclonal antibody
- Clone numberPolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Factor VIIIa light chain
- Tested ApplicationsWB, IHC-P, IF(IHC-P)
- Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
- Cross reactivityHuman
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the target antigenThis gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
- Synonym namescoagulation factor VIII; Ahf; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII associated protein b; Coagulation factor VIII isoform b; Coagulation factor VIII procoagulent component; Coagulation factor VIIIc; Dna segment on chromosome x unique 1253 expressed sequence; Dxs1253e; F8; F8 protein; F8b; F8c; FactorVIII; FVIII; Hema; Hema coagulation factor VIIIc procoagulent component; Hemophilia a; Hemophilia classic; OTTHUMP00000061446; Procoagulant component; AHF; DXS1253E; F8B; F8C; FVIII; HEMA; FA8_HUMAN.
- Gene targetFactor VIIIa light chain
- isotype filter
- Immunoglobulin G IgG
- technique filter
- Antibody
- light
- TechniqueAntibody, light, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies