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Cofilin (Tyr140) Antibody

  • Catalog number
    bs-5258R
  • Product name
    Cofilin (Tyr140) Antibody
  • Size
    0.1ml
  • Short name
    Anti-Cofilin Tyr140
  • Long name
    Cofilin (Tyr140) Primary Polyclonal Antibody
  • Also known as
    Cofilin (Tyr140) PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Cofilin Tyr140
  • Specificity
    This is a highly specific antibody against Cofilin Tyr140.
  • Modification s
    Phosphorylation
  • Modification site s
    Tyr140
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    135-142/166
  • Subcellular location
    Intracellular
  • Source
    KLH conjugated synthetic phosphopeptide derived from human Cofilin around the phosphorylation site of Tyr140
  • Gene ID number
    1072
  • Swiss Prot
    P23528
  • Tested Applications
    WB, IHC-P, IF(IHC-P)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    CFL; cofilin; HEL-S-15; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin, non-muscle isoform; CFL1
  • Gene target
    Cofilin Tyr140
  • isotype filter
    • Immunoglobulin G IgG
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies