- Catalog numberbsm-50178M
- Product nameCDK5 (8A1) Monoclonal Antibody
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-CDK5
- Long nameCDK5 (8A1) Monoclonal Antibody
- Also known asCDK5 (8A1) Monoclonal Antibody
- CategoryPrimary Antibodies
- ConjugationUnconjugated
- HostMouse (Mus musculus)
- Target AntigenCDK5
- SpecificityThis is a highly specific antibody against CDK5.
- Modification sNone
- Modification site sUnmodified antibody
- ClonalityMonoclonal
- Clone number8A1
- IsotypeImmunoglobulin G (IgG)2b κ
- SourceHis-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells.
- Gene ID number1020
- Swiss ProtQ00535
- Tested ApplicationsWB, IP
- Recommended dilutionsWB (1:1000 ~ 2000) IP (2 ul)
- Cross reactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the target antigenCyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in kidney, testes, and ovary. And Its activity is detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits called p35 and p39. The two activators regulate the spatial and temporal expression of active Cdk5 to restrict its activity primarily to post-mitotic neurons.
- Purification methodAmmonium sulfate precipitation
- Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
- Synonym namesLIS7; PSSALRE; Cyclin-dependent-like kinase 5; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit; CDK5; CDKN5
- Alternative to gene target
- [ "cyclin-dependent kinase 5", "PSSALRE", "CDK5 and IDBG-48977 and ENSG00000164885 and 1020", "transferase activity", "nuclei", "Cdk5 and IDBG-141112 and ENSMUSG00000028969 and 12568", "CDK5 and IDBG-637527 and ENSBTAG00000007766 and 281066" ]
- Gene targetCDK5 8A1 Monoclonal
- Gene symbolCDK5
- isotype filter
- Immunoglobulin G IgG 2b κ
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
- Alternative techniqueantibodies