• Catalog number
    bsm-50178M
  • Product name
    CDK5 (8A1) Monoclonal Antibody
  • Size
    0.1ml
  • Short name
    Anti-CDK5
  • Long name
    CDK5 (8A1) Monoclonal Antibody
  • Also known as
    CDK5 (8A1) Monoclonal Antibody
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Mouse (Mus musculus)
  • Target Antigen
    CDK5
  • Specificity
    This is a highly specific antibody against CDK5.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Monoclonal
  • Clone number
    8A1
  • Isotype
    Immunoglobulin G (IgG)2b κ
  • Source
    His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells.
  • Gene ID number
    1020
  • Swiss Prot
    Q00535
  • Tested Applications
    WB, IP
  • Recommended dilutions
    WB (1:1000 ~ 2000) IP (2 ul)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in kidney, testes, and ovary. And Its activity is detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits called p35 and p39. The two activators regulate the spatial and temporal expression of active Cdk5 to restrict its activity primarily to post-mitotic neurons.
  • Purification method
    Ammonium sulfate precipitation
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    LIS7; PSSALRE; Cyclin-dependent-like kinase 5; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit; CDK5; CDKN5
  • Alternative to gene target
    • [ "cyclin-dependent kinase 5", "PSSALRE", "CDK5 and IDBG-48977 and ENSG00000164885 and 1020", "transferase activity", "nuclei", "Cdk5 and IDBG-141112 and ENSMUSG00000028969 and 12568", "CDK5 and IDBG-637527 and ENSBTAG00000007766 and 281066" ]
  • Gene target
    CDK5 8A1 Monoclonal
  • Gene info
  • Gene symbol
    CDK5
  • isotype filter
    • Immunoglobulin G IgG 2b κ
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
  • Alternative technique
    antibodies