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BNP(H1G3) Monoclonal Antibody

  • Catalog number
    bsm-4579M
  • Product name
    BNP(H1G3) Monoclonal Antibody
  • Size
    0.1ml
  • Short name
    Anti-BNP
  • Long name
    BNP(H1G3) Monoclonal Antibody
  • Also known as
    BNP(H1G3) Monoclonal Antibody
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Mouse (Mus musculus)
  • Target Antigen
    BNP
  • Specificity
    This is a highly specific antibody against BNP.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Monoclonal
  • Clone number
    H1G3
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BNP
  • Gene ID number
    4879
  • Tested Applications
    WB, IHC-P, IF(IHC-P)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
  • Purification method
    Purified by Protein G.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    BNP 32; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein.
  • Gene target
    BNP H1G3 Monoclonal
  • isotype filter
    • Immunoglobulin G IgG
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
  • Alternative technique
    antibodies