- Catalog numberbs-5848R
- Product nameADAM15 Antibody
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-ADAM15
- Long nameADAM15 Primary Polyclonal Antibody
- Also known asADAM15 PAb
- CategoryPrimary Antibodies
- ConjugationUnconjugated
- HostRabbit (Oryctolagus cuniculus)
- Target AntigenADAM15
- SpecificityThis is a highly specific antibody against ADAM15.
- Modification sNone
- Modification site sUnmodified antibody
- ClonalityPolyclonal antibody
- Clone numberPolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Subcellular locationExtracellular
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAM15
- Gene ID number8751
- Tested ApplicationsWB, FCM, IHC-P, IF(IHC-P)
- Recommended dilutionsWB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
- Cross reactivityHuman
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the target antigenADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
- Synonym namesA disintegrin and metalloproteinase domain 15; ADA15_HUMAN; ADAM 15; ADAM metallopeptidase domain 15; Adam15; and cysteine-rich protein 15; Disintegrin and metalloproteinase domain-containing protein 15; disintegrin-like; EC 3.4.24.; MDC 15; MDC-15; MDC15; Metalloprotease RGD disintegrin protein; Metalloproteinase like disintegrin like and cysteine rich protein 15; Metalloproteinase-like; Metargidin.
- Alternative to gene target
- [ "ADAM metallopeptidase domain 15", "MDC15", "ADAM15 and IDBG-103072 and ENSG00000143537 and 8751", "SH3 domain binding", "Cell surfaces", "Adam15 and IDBG-163900 and ENSMUSG00000028041 and 11490", "ADAM15 and IDBG-632243 and ENSBTAG00000010663 and 784605" ]
- Gene targetADAM15
- Identity:HGNC:193
- Gene:ADAM15
- Long gene name:ADAM metallopeptidase domain 15
- Synonyms gene name:a disintegrin and metalloproteinase domain 15 (metargidin)
- Synonyms:MDC15
- Discovery year:1998-12-01
- Entrez gene record:8751
- Pubmed identification:9516430
- RefSeq identity:NM_003815
- Classification:ADAM metallopeptidase domain containing
- VEGA ID:OTTHUMG00000013898
- Gene symbolADAM15
- isotype filter
- Immunoglobulin G IgG
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies