• Catalog number
    bsm-50196M
  • Product name
    α2-macroglobulin (3D1) Monoclonal Antibody
  • Size
    0.1ml
  • Short name
    Anti-α2-macroglobulin
  • Long name
    α2-macroglobulin (3D1) Monoclonal Antibody
  • Also known as
    α2-macroglobulin (3D1) Monoclonal Antibody
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Mouse (Mus musculus)
  • Target Antigen
    α2-macroglobulin
  • Specificity
    This is a highly specific antibody against α2-macroglobulin.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Monoclonal
  • Clone number
    3D1
  • Isotype
    Immunoglobulin G (IgG)1 κ
  • Source
    α2-macroglobulin protein purified from Human plasma
  • Gene ID number
    2
  • Swiss Prot
    P01023
  • Tested Applications
    IP
  • Recommended dilutions
    IP (1ug)
  • Cross reactivity
    Human
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
  • Purification method
    Ammonium sulfate precipitation
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    A2MD; CPAMD5; FWP007; S863-7; Alpha-2-macroglobulin; Alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; A2M
  • Gene target
    α2-macroglobulin 3D1 Monoclonal
  • isotype filter
    • Immunoglobulin G IgG 1 κ
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
  • Alternative technique
    antibodies