- Catalog numberbsm-50196M
- Product nameα2-macroglobulin (3D1) Monoclonal Antibody
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-α2-macroglobulin
- Long nameα2-macroglobulin (3D1) Monoclonal Antibody
- Also known asα2-macroglobulin (3D1) Monoclonal Antibody
- CategoryPrimary Antibodies
- ConjugationUnconjugated
- HostMouse (Mus musculus)
- Target Antigenα2-macroglobulin
- SpecificityThis is a highly specific antibody against α2-macroglobulin.
- Modification sNone
- Modification site sUnmodified antibody
- ClonalityMonoclonal
- Clone number3D1
- IsotypeImmunoglobulin G (IgG)1 κ
- Sourceα2-macroglobulin protein purified from Human plasma
- Gene ID number2
- Swiss ProtP01023
- Tested ApplicationsIP
- Recommended dilutionsIP (1ug)
- Cross reactivityHuman
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the target antigenIs able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
- Purification methodAmmonium sulfate precipitation
- Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
- Synonym namesA2MD; CPAMD5; FWP007; S863-7; Alpha-2-macroglobulin; Alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; A2M
- Gene targetα2-macroglobulin 3D1 Monoclonal
- isotype filter
- Immunoglobulin G IgG 1 κ
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
- Alternative techniqueantibodies