- Catalog numberbs-10387R-HRP
- Product nameThrombin Activation peptide fragment 1 Antibody, HRP Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-Thrombin Activation peptide fragment 1
- Long nameThrombin Activation peptide fragment 1 Antibody, HRP Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationHRP
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenThrombin Activation peptide fragment 1
- SpecificityThis is a highly specific antibody against Thrombin Activation peptide fragment 1.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG), Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic peptide derived from human Thrombin Activation peptide fragment 1
- Gene ID number2147
- Tested applicationsWB, IHC-P
- Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundThrombin is the final protease in the blood coagulation cascade and serves both pro- and anticoagulant functions through the cleavage of several targets. The ability of thrombin to specifically recognize a wide range of substrates derives from interactions which occur outside of the active site of thrombin. Thrombin possesses two anion binding exosites which mediate many of its interactions with cofactors and substrates, and although many structures of thrombin have been solved, few such interactions have been described in molecular detail. Glycosaminoglycan binding to exosite II of thrombin plays a major role in switching off the procoagulant functions of thrombin by mediating its irreversible inhibition by circulating serpins and by its binding to the endothelial cell surface receptor thrombomodulin.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation EmissionN/A
- SynonymsActivation peptide fragment 1; coagulation factor II; prothrombin; F2; Cf-2; Cf2; FII; F 2; coagulation factor II thrombin; Coagulation factor II; Coagulation factor II precursor; F2; Factor II; Factor-II; Prothrombin; prothrombin B-chain; PT; serine protease; THRB; THRB_HUMAN; Thrombin.
- Gene targetThrombin Activation peptide 1 Conjugated
- isotype filter
- Immunoglobulin G IgG
- LabelHRP
- label filter
- HRP
- technique filter
- activation
- Antibody
- peptide
- Techniqueactivation, Antibody, peptide, antibodies against human proteins, antibodies for, antibody Conjugates, peptides
- Alternative techniqueantibodies, peptides