- Catalog numberbs-10111R-Cy3
- Product nameTau protein(Ser552) Antibody, Cy3 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-Tau protein Ser552
- Long nameTau protein(Ser552) Polyclonal Antibody, Cy3 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy3
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenTau protein Ser552
- SpecificityThis is a highly specific antibody against Tau protein Ser552.
- ModificationPhosphorylation
- Modification siteSer552
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser552
- Gene ID number4137
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundTau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission512,550nm/570,615nm
- SynonymsTauSer552; MAPTphospho 235;DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPT; MAPTL; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PPND; pTau; TAU_HUMAN; RNPTAU; Tauopathy and respiratory failure, included.
- Gene targetTau protein Ser552 Conjugated
- isotype filter
- Immunoglobulin G IgG
- LabelCy3
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- Cy3
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- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies