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SLK (Tyr530) Antibody, Cy7 Conjugated

  • Catalog number
    bs-5332R-Cy7
  • Product name
    SLK (Tyr530) Antibody, Cy7 Conjugated
  • Size
    0.1ml
  • Short name
    Anti-SLK Tyr530
  • Long name
    SLK (Tyr530) Polyclonal Antibody, Cy7 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy7
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    SLK Tyr530
  • Specificity
    This is a highly specific antibody against SLK Tyr530.
  • Modification
    Phosphorylation
  • Modification site
    Tyr530
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic phosphopeptide derived from human FYN around the phosphorylation site of Tyr530
  • Gene ID number
    2534
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1. The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR. Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    743nm/767nm
  • Synonyms
    Fyn phospho Y530; p-Fyn phospho Y530; C syn protooncogene; FYN oncogene related to SRC FGR YESï¼› MGC45350ï¼› OKT3 induced calcium influx regulatorï¼› P59 FYN; Protein tyrosine kinase fyn; Proto oncogene tyrosine protein kinase fyn; Protooncogene Syn; SLK; Src like kinase; Src yes related novel gene; Src/yes related novel gene; SYN; FYN; Tyrosine kinase p59fyn T; Tyrosine kinase p59fynT.
  • Alternative to gene target
    • [ "STE20-like kinase", "bA16H23.1 and LOSK and se20-9 and STK2", "SLK and IDBG-88663 and ENSG00000065613 and 9748", "transferase activity", "Cytoplasm", "Slk and IDBG-174800 and ENSMUSG00000025060 and 20874", "SLK and IDBG-639375 and ENSBTAG00000001017 and 535342" ]
  • Gene target
    SLK Tyr530 Conjugated
    • Gene info
    Gene info
  • Gene symbol
    FYN, SLK
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    Cy7
  • label filter
    • Cy7
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies