- Catalog numberbs-3382R-Biotin
- Product nameRASGRF1 (Ser916) Antibody, Biotin Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-RASGRF1 Ser916
- Long nameRASGRF1 (Ser916) Polyclonal Antibody, Biotin Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationBiotin
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenRASGRF1 Ser916
- SpecificityThis is a highly specific antibody against RASGRF1 Ser916.
- ModificationPhosphorylation
- Modification siteSer916
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic phosphopeptide derived from mouse RasGRF1 around the phosphorylation site of Ser916
- Gene ID number5923
- Tested applicationsWB, IHC-P
- Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation EmissionN/A
- SynonymsRASGRF1phospho S916CDC25; CDC25L; GNRP; GRF1; GRF55; Guanine nucleotide exchange factor; Guanine nucleotide releasing factor 55 kD; Guanine nucleotide releasing protein; HGRF55; PP13187; Ras protein specic guanine nucleotide releasing factor 1; Ras specic guanine nucleotide releasing factor; Ras specic guanine nucleotide releasing factor CDC25 homolog; Ras specic nucleotide exchange factor CDC25.
- Alternative to gene target
- [ "Ras protein-specific guanine nucleotide-releasing factor 1", "CDC25 and CDC25L and GNRP and GRF1 and GRF55 and H-GRF55 and PP13187 and ras-GRF1", "RASGRF1 and IDBG-25346 and ENSG00000058335 and 5923", "glutamate receptor binding", "Plasma membranes", "Rasgrf1 and IDBG-190479 and ENSMUSG00000032356 and 19417", "RASGRF1 and IDBG-630181 and ENSBTAG00000019940 and 520039" ]
- Gene targetRASGRF1 Ser916 Conjugated
- Identity:HGNC:9875
- Gene:RASGRF1
- Long gene name:Ras protein specific guanine nucleotide releasing factor 1
- Synonyms:CDC25LCDC25GRF55H-GRF55GNRPPP13187
- Discovery year:1994-02-11
- Entrez gene record:5923
- Pubmed identification:7684828, 1379731
- RefSeq identity:NM_002891
- Classification:Dbl family Rho GEFs, Pleckstrin homology domain containing
- VEGA ID:OTTHUMG00000144172
- Gene symbolRASGRF1
- isotype filter
- Immunoglobulin G IgG
- LabelBiotin
- label filter
- Biotin
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies