RASGRF1 (Ser916) Antibody, Biotin Conjugated

• Catalog number
  bs-3382R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  RASGRF1 (Ser916) Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  RASGRF1 Ser916
• Specificity
  This is a highly specific antibody against RASGRF1 Ser916.
• Modification
  Phosphorylation
• Modification site
  Ser916
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from mouse RasGRF1 around the phosphorylation site of Ser916
• Gene ID number
  5923
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  RASGRF1phospho S916CDC25; CDC25L; GNRP; GRF1; GRF55; Guanine nucleotide exchange factor; Guanine nucleotide releasing factor 55 kD; Guanine nucleotide releasing protein; HGRF55; PP13187; Ras protein specic guanine nucleotide releasing factor 1; Ras specic guanine nucleotide releasing factor; Ras specic guanine nucleotide releasing factor CDC25 homolog; Ras specic nucleotide exchange factor CDC25.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  RASGRF1   Ser916   Conjugated  
• Gene symbol
  RASGRF1
• Short name
  Anti-RASGRF1 Ser916
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-RASGRF1 Ser916 PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  Ras protein-specific guanine nucleotide-releasing factor 1, CDC25 and CDC25L and GNRP and GRF1 and GRF55 and H-GRF55 and PP13187 and ras-GRF1, RASGRF1 and IDBG-25346 and ENSG00000058335 and 5923, glutamate receptor binding, Plasma membranes, Rasgrf1 and IDBG-190479 and ENSMUSG00000032356 and 19417, RASGRF1 and IDBG-630181 and ENSBTAG00000019940 and 520039

Gene info

• Identity
  HGNC:9875
• Gene
  RASGRF1
• Long gene name
  Ras protein specific guanine nucleotide releasing factor 1
• Synonyms gene
  • GRF1
• Synonyms
  • CDC25L
  • CDC25
  • GRF55
  • H-GRF55
  • GNRP
  • PP13187
• Synonyms name
  • CDC25 like (S. cerevisiae)
• GenBank acession
  • M91815
• Locus
  15q25.1
• Discovery year
  1994-02-11
• Entrez gene record
  5923
• Pubmed identfication
  • 7684828
  • 1379731
• RefSeq identity
  • NM_002891
• Classification
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000144172

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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