- Catalog numberbs-3343R-Cy5
- Product namePLC gamma 1 (Tyr783) Antibody, Cy5 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-PLC gamma 1 Tyr783
- Long namePLC gamma 1 (Tyr783) Polyclonal Antibody, Cy5 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy5
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenPLC gamma 1 Tyr783
- SpecificityThis is a highly specific antibody against PLC gamma 1 Tyr783. This phosphorylation site is homologous across the listed species.
- ModificationPhosphorylation
- Modification siteTyr783
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range760-810/1290
- Subcellular locationCytoplasm
- SourceKLH conjugated synthetic phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr783
- Gene ID number5335
- Swiss ProtP19174
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundMediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission625,650nm/670nm
- SynonymsPLC1; NCKAP3; PLC-II; PLC148; PLCgamma1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; Phospholipase C-gamma-1; PLC-gamma-1; PLCG1
- Gene targetPLC gamma 1 Tyr783 Conjugated
- Identity:HGNC:15917
- Gene:PLCB1
- Long gene name:phospholipase C beta 1
- Synonyms gene name:phospholipase C, beta 1 (phosphoinositide-specific)
- Synonyms:KIAA0581PLC-IPLC154
- Discovery year:2001-06-21
- Entrez gene record:23236
- Pubmed identification:10760467, 11118617
- Classification:Phospholipases, C2 domain containing phospholipases
- VEGA ID:OTTHUMG00000031849
- Identity:HGNC:9063
- Gene:PLCL1
- Long gene name:phospholipase C like 1 (inactive)
- Synonyms gene name:phospholipase C, epsilon, phospholipase C-like 1, phospholipase C like 1
- Synonyms:PLC-L, PLCL, PRIPPPP1R127
- Discovery year:1995-12-12
- Entrez gene record:5334
- Pubmed identification:7633416
- RefSeq identity:NM_006226
- Classification:Protein phosphatase 1 regulatory subunits, C2 domain containing phospholipases
- VEGA ID:OTTHUMG00000132750
- Identity:HGNC:9065
- Gene:PLCG1
- Long gene name:phospholipase C gamma 1
- Synonyms gene name:phospholipase C, gamma 1 (formerly subtype 148), phospholipase C, gamma 1
- Synonyms:PLC148, PLC-IIPLCgamma1NCKAP3
- Discovery year:1989-05-31
- Entrez gene record:5335
- Pubmed identification:2167438, 3254788
- RefSeq identity:NM_182811
- Classification:Pleckstrin homology domain containing, MicroRNA protein coding host genes, Phospholipases, SH2 domain containing, C2 domain containing phospholipases, EF-hand domain containing
- VEGA ID:OTTHUMG00000033082
- Identity:HGNC:29037
- Gene:PLCH2
- Long gene name:phospholipase C eta 2
- Synonyms gene name:phospholipase C-like 4, phospholipase C, eta 2
- Synonyms:KIAA0450, PLCeta2RP3-395M20.1PLC-eta2
- Discovery year:2004-07-28
- Entrez gene record:9651
- Pubmed identification:15899900
- RefSeq identity:NM_014638
- Classification:EF-hand domain containing, Phospholipases
- VEGA ID:OTTHUMG00000000719
- Identity:HGNC:4606
- Gene:PDIA3
- Long gene name:protein disulfide isomerase family A member 3
- Synonyms gene name:glucose regulated protein, 58kDa, protein disulfide isomerase-associated 3, protein disulfide isomerase family A, member 3
- Synonyms:P58, ERp61, ERp57ERp60GRP57PI-PLCHsT17083
- Discovery year:1997-06-09
- Entrez gene record:2923
- Pubmed identification:8974399
- RefSeq identity:NM_005313
- Classification:Protein disulfide isomerases
- VEGA ID:OTTHUMG00000044444
- Gene symbolPLCB1, PLCL1, PLCG1, PLCH2, PDIA3
- isotype filter
- Immunoglobulin G IgG
- LabelCy5
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- Cy5
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies