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NCAM2 Antibody, Cy5.5 Conjugated

  • Catalog number
    bs-11094R-Cy5.5
  • Product name
    NCAM2 Antibody, Cy5.5 Conjugated
  • Size
    0.1ml
  • Short name
    Anti-NCAM2
  • Long name
    NCAM2 Polyclonal Antibody, Cy5.5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy5.5
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    NCAM2
  • Specificity
    This is a highly specific antibody against NCAM2.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Subcellular location
    Extracellular
  • Source
    KLH conjugated synthetic peptide derived from human NCAM2
  • Tested applications
    FCM, IF(IHC-P)
  • Recommended dilutions
    FCM(1:20-100), IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human adult and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line; this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    675nm/694nm
  • Synonyms
    N CAM 2; N CAM 21; N CAM2; N CAM21; N-CAM-2; NCAM 2; NCAM 21; NCAM-2; Ncam2; NCAM2_HUMAN; NCAM21; Neural cell adhesion molecule 2; OCAM GPI; R4B12; RB 8 neural cell adhesion molecule; RB8 neural cell adhesion molecule; RNCAM.
  • Alternative to gene target
    • [ "neural cell adhesion molecule 2", "NCAM21", "NCAM2 and IDBG-1027 and ENSG00000154654 and 4685", "protein binding", "Plasma membranes", "Ncam2 and IDBG-172510 and ENSMUSG00000022762 and 17968", "NCAM2 and IDBG-630332 and ENSBTAG00000003301 and 535613" ]
  • Gene target
    NCAM2 Conjugated
    • Gene info
    • Identity:HGNC:7657
    • Gene:NCAM2
    • Long gene name:neural cell adhesion molecule 2
    • Synonyms:NCAM21MGC51008
    • Discovery year:1997-04-25
    • Entrez gene record:4685
    • Pubmed identification:9226371
    • RefSeq identity:NM_004540
    • Classification:Ig-like cell adhesion molecule family, I-set domain containing, Fibronectin type III domain containing
    • VEGA ID:OTTHUMG00000078121
  • Gene symbol
    NCAM2
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    Cy5.5
  • label filter
    • Cy5.5
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies