- Catalog numberbs-5474R-Cy3
- Product nameMBP(Thr232) Antibody, Cy3 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-MBP Thr232
- Long nameMBP(Thr232) Polyclonal Antibody, Cy3 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy3
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenMBP Thr232
- SpecificityThis is a highly specific antibody against MBP Thr232. This antibody recognizes Thr229 in mice and Thr122 in rat
- ModificationPhosphorylation
- Modification siteThr232
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range225-235/304
- Subcellular locationCytoplasm
- SourceKLH conjugated synthetic phosphopeptide derived from human MBP around the phosphorylation site of Thr232
- Gene ID number4155
- Swiss ProtP02686
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundThe classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission512,550nm/570,615nm
- SynonymsMyelin basic protein; MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein
- Gene targetMBP Thr232 Conjugated
- Identity:HGNC:6925
- Gene:MBP
- Long gene name:myelin basic protein
- Discovery year:1986-01-01
- Entrez gene record:4155
- Pubmed identification:2425357
- RefSeq identity:NM_001025081
- VEGA ID:OTTHUMG00000132874
- Identity:HGNC:9362
- Gene:PRG2
- Long gene name:proteoglycan 2, pro eosinophil major basic protein
- Synonyms gene name:proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
- Synonyms:MBPBMPGproMBP
- Discovery year:1993-09-29
- Entrez gene record:5553
- Pubmed identification:1565101
- RefSeq identity:NM_002728
- Classification:C-type lectin domain containing
- VEGA ID:OTTHUMG00000167027
- Identity:HGNC:3350
- Gene:ENO1
- Long gene name:enolase 1
- Synonyms gene name:enolase 1, (alpha)
- Synonyms:PPHMBP-1
- Discovery year:1989-04-21
- Entrez gene record:2023
- Pubmed identification:9653645, 9691177
- RefSeq identity:NM_001428
- Classification:Enolases, MicroRNA protein coding host genes
- VEGA ID:OTTHUMG00000001773
- Identity:HGNC:4921
- Gene:HIVEP2
- Long gene name:HIVEP zinc finger 2
- Synonyms gene name:human immunodeficiency virus type I enhancer-binding protein 2, human immunodeficiency virus type I enhancer binding protein 2
- Synonyms:MBP-2, HIV-EP2MIBP1ZAS2Schnurri-2ZNF40B
- Discovery year:1992-10-21
- Entrez gene record:3097
- Pubmed identification:1733857, 2022670
- Classification:Zinc fingers C2H2-type
- VEGA ID:OTTHUMG00000015713
- Identity:HGNC:4920
- Gene:HIVEP1
- Long gene name:HIVEP zinc finger 1
- Synonyms gene name:human immunodeficiency virus type I enhancer-binding protein 1, zinc finger protein 40, human immunodeficiency virus type I enhancer binding protein 1
- Synonyms:CIRIP, MBP-1, CRYBP1PRDII-BF1ZAS1Schnurri-1ZNF40A
- Discovery year:1990-10-04
- Entrez gene record:3096
- Pubmed identification:2108316, 2037300, 2504707
- RefSeq identity:NM_002114
- Classification:Zinc fingers C2H2-type
- VEGA ID:OTTHUMG00000014265
- Gene symbolMBP, PRG2, ENO1, HIVEP2, HIVEP1
- isotype filter
- Immunoglobulin G IgG
- Labelmbp
- label filter
- mbp
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies
Gene info
Gene info
Gene info
Locus Specific Databases:LRG_1165