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HIF2 alpha Antibody, Cy7 Conjugated

  • Catalog number
    bs-1447R-Cy7
  • Product name
    HIF2 alpha Antibody, Cy7 Conjugated
  • Size
    0.1ml
  • Short name
    Anti-HIF2 alpha
  • Long name
    HIF2 alpha Polyclonal Antibody, Cy7 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy7
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    HIF2 alpha
  • Specificity
    This is a highly specific antibody against HIF2 alpha.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    1-50/874
  • Subcellular location
    Nucleus
  • Source
    KLH conjugated synthetic peptide derived from mouse HIF2 Alpha
  • Gene ID number
    13819
  • Swiss Prot
    P97481
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP3. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity).
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    743nm/767nm
  • Synonyms
    HLF; HRF; MOP2; HIF2A; bHLHe73; HIF-2alpha; Endothelial PAS domain-containing protein 1; EPAS-1; HIF-1-alpha-like factor; mHLF; HIF-related factor; Hypoxia-inducible factor 2-alpha; HIF-2-alpha; HIF2-alpha; Epas1
  • Gene target
    HIF2 alpha Conjugated
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    Cy7
  • label filter
    • Cy7
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies