- Catalog numberbs-3073R-Cy5
- Product nameHDAC4(Ser246)/HDAC5(Ser259)/HDAC7(Ser155) Antibody, Cy5 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155
- Long nameHDAC4(Ser246)/HDAC5(Ser259)/HDAC7(Ser155) Antibody, Cy5 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy5
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenHDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155
- SpecificityThis is a highly specific antibody against HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155.
- ModificationPhosphorylation
- Modification siteSer155
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser246
- Gene ID number9759
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission625,650nm/670nm
- SynonymsHDAC4Ser246; HDAC5Ser259; HDAC7Ser155; HD 4; HD4; HDAC 4; HDAC A; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288; EC 3.5.1.98; HA6116; p-HDAC4Ser246; p-HDAC5Ser259; p-HDAC7Ser155.
- Alternative to gene target
- [ "histone deacetylase 7", "HDAC7 and IDBG-29060 and ENSG00000061273 and 51564", "NAD-dependent histone deacetylase activity (H3-K18 specific)", "nuclei", "Hdac7 and IDBG-179042 and ENSMUSG00000022475 and 56233", "HDAC7 and IDBG-633011 and ENSBTAG00000026819 and 509843" ]
- [ "histone deacetylase 5", "HD5 and NY-CO-9", "HDAC5 and IDBG-53295 and ENSG00000108840 and 10014", "NAD-dependent histone deacetylase activity (H3-K18 specific)", "nuclei", "Hdac5 and IDBG-212520 and ENSMUSG00000008855 and 15184", "HDAC5 and IDBG-640847 and ENSBTAG00000016254 and 504242" ]
- [ "histone deacetylase 4", "AHO3 and BDMR and HA6116 and HD4 and HDAC-4 and HDAC-A and HDACA", "HDAC4 and IDBG-84594 and ENSG00000068024 and 9759", "NAD-dependent histone deacetylase activity (H3-K18 specific)", "nuclei", "Hdac4 and IDBG-181579 and ENSMUSG00000026313 and 208727", "HDAC4 and IDBG-642244 and ENSBTAG00000017764 and 517559" ]
- Gene targetHDAC4 Ser246 /HDAC5 Ser259 /HDAC7 Ser155 Conjugated
- Identity:HGNC:54064
- Gene:HDAC4-AS1
- Long gene name:HDAC4 antisense RNA 1
- Discovery year:2018-09-27
- Entrez gene record:101928111
- RefSeq identity:NR_135575
- Classification:Antisense RNAs
- Identity:HGNC:14067
- Gene:HDAC7
- Long gene name:histone deacetylase 7
- Synonyms gene name:histone deacetylase 7A
- Synonyms:DKFZP586J0917
- Discovery year:2001-07-13
- Entrez gene record:51564
- Pubmed identification:10922406, 10640276
- Classification:Histone deacetylases, class IIA
- VEGA ID:OTTHUMG00000152968
- Identity:HGNC:14068
- Gene:HDAC5
- Long gene name:histone deacetylase 5
- Synonyms:KIAA0600NY-CO-9FLJ90614
- Discovery year:2000-11-28
- Entrez gene record:10014
- Pubmed identification:10220385, 9610721
- RefSeq identity:NM_001015053
- Classification:Histone deacetylases, class IIA
- VEGA ID:OTTHUMG00000181806
- Identity:HGNC:14063
- Gene:HDAC4
- Long gene name:histone deacetylase 4
- Synonyms gene name:brachydactyly-mental retardation syndrome
- Synonyms:KIAA0288HDAC-AHDACAHD4HA6116HDAC-4
- Discovery year:2000-11-28
- Entrez gene record:9759
- Pubmed identification:10206986, 10220385, 20691407
- RefSeq identity:NM_006037
- Classification:Histone deacetylases, class IIA, MicroRNA protein coding host genes
- VEGA ID:OTTHUMG00000133344
- Gene symbolHDAC4-AS1, HDAC7, HDAC5, HDAC4
- isotype filter
- Immunoglobulin G IgG
- LabelCy5
- label filter
- Cy5
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies