HDAC4(Ser246)/HDAC5(Ser259)/HDAC7(Ser155) Antibody, Cy5 Conjugated

• Catalog number
  bs-3073R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  HDAC4(Ser246)/HDAC5(Ser259)/HDAC7(Ser155) Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155
• Specificity
  This is a highly specific antibody against HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155.
• Modification
  Phosphorylation
• Modification site
  Ser155
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser246
• Gene ID number
  9759
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  HDAC4Ser246; HDAC5Ser259; HDAC7Ser155; HD 4; HD4; HDAC 4; HDAC A; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288; EC 3.5.1.98; HA6116; p-HDAC4Ser246; p-HDAC5Ser259; p-HDAC7Ser155.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  HDAC4   Ser246   HDAC5   Ser259   HDAC7   Ser155   Conjugated  
• Gene symbol
  HDAC4-AS1, HDAC7, HDAC5, HDAC4
• Short name
  Anti-HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155 PAb Cy5
• Alternative technique
  antibodies
• Alternative to gene target
  histone deacetylase 7, HDAC7 and IDBG-29060 and ENSG00000061273 and 51564, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac7 and IDBG-179042 and ENSMUSG00000022475 and 56233, HDAC7 and IDBG-633011 and ENSBTAG00000026819 and 509843

Gene info

• Identity
  HGNC:54064
• Gene
  HDAC4-AS1
• Long gene name
  HDAC4 antisense RNA 1
• Locus
  2q37.3
• Discovery year
  2018-09-27
• Entrez gene record
  101928111
• RefSeq identity
  • NR_135575
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:14067
• Gene
  HDAC7
• Long gene name
  histone deacetylase 7
• Synonyms gene
  • HDAC7A
• Synonyms gene name
  • histone deacetylase 7A
• Synonyms
  • DKFZP586J0917
• GenBank acession
  • AF239243
• Locus
  12q13.11
• Discovery year
  2001-07-13
• Entrez gene record
  51564
• Pubmed identfication
  • 10922406
  • 10640276
• Classification
  • Histone deacetylases, class IIA
• VEGA ID
  OTTHUMG00000152968

Gene info

• Identity
  HGNC:14068
• Gene
  HDAC5
• Long gene name
  histone deacetylase 5
• Synonyms
  • KIAA0600
  • NY-CO-9
  • FLJ90614
• GenBank acession
  • AF249731
• Locus
  17q21.31
• Discovery year
  2000-11-28
• Entrez gene record
  10014
• Pubmed identfication
  • 10220385
  • 9610721
• RefSeq identity
  • NM_001015053
• Classification
  • Histone deacetylases, class IIA
• VEGA ID
  OTTHUMG00000181806

Gene info

• Identity
  HGNC:14063
• Gene
  HDAC4
• Long gene name
  histone deacetylase 4
• Synonyms gene
  • BDMR
• Synonyms gene name
  • brachydactyly-mental retardation syndrome
• Synonyms
  • KIAA0288
  • HDAC-A
  • HDACA
  • HD4
  • HA6116
  • HDAC-4
• GenBank acession
  • AB006626
• Locus
  2q37.3
• Discovery year
  2000-11-28
• Entrez gene record
  9759
• Pubmed identfication
  • 10206986
  • 10220385
  • 20691407
• RefSeq identity
  • NM_006037
• Classification
  • Histone deacetylases, class IIA
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133344

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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