- Catalog numberbs-11645R-HRP
- Product nameFISH Antibody, HRP Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-FISH
- Long nameFISH Polyclonal Antibody, HRP Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationHRP
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenFISH
- SpecificityThis is a highly specific antibody against FISH.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic peptide derived from human FISH
- Tested applicationsIHC-P
- Recommended dilutionsIHC-P(1:100-500)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundFish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation EmissionN/A
- SynonymsAdapter protein TKS5; Five SH3 domain-containing protein; SH3 and PX domain-containing protein 2A; SH3 multiple domains protein 1; Sh3md1; Sh3pxd2a; SPD2A_HUMAN; TKs5; Tyrosine kinase substrate with five SH3 domains.
- Gene targetFISH Conjugated
- Identity:HGNC:23664
- Gene:SH3PXD2A
- Long gene name:SH3 and PX domains 2A
- Synonyms gene name:SH3 multiple domains 1
- Synonyms:FISHKIAA0418
- Discovery year:2003-12-01
- Entrez gene record:9644
- Pubmed identification:9687503
- RefSeq identity:NM_014631
- VEGA ID:OTTHUMG00000018997
- Gene symbolSH3PXD2A
- isotype filter
- Immunoglobulin G IgG
- LabelHRP
- label filter
- HRP
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies