- Catalog numberbs-13720R-Cy3
- Product nameFAM48A Antibody, Cy3 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-FAM48A
- Long nameFAM48A Polyclonal Antibody, Cy3 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy3
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenFAM48A
- SpecificityThis is a highly specific antibody against FAM48A.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic peptide derived from human FAM48A
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundFAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4% of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission512,550nm/570,615nm
- SynonymsFAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4% of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.
- Gene targetFAM48A Conjugated
- Identity:HGNC:20596
- Gene:SUPT20H
- Long gene name:SPT20 homolog, SAGA complex component
- Synonyms gene name:chromosome 13 open reading frame 19, family with sequence similarity 48, member A, suppressor of Ty 20 homolog (S. cerevisiae)
- Synonyms:SPT20, bA421P11.4, P38IP
- Discovery year:2004-04-16
- Entrez gene record:55578
- Pubmed identification:12070015, 16685401, 19114550
- RefSeq identity:NM_017569
- Classification:SAGA complex
- VEGA ID:OTTHUMG00000016747
- Gene symbolSUPT20H
- isotype filter
- Immunoglobulin G IgG
- LabelCy3
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- Cy3
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies