- Catalog numberbs-13131R-Cy3
- Product nameFactor I light chain Antibody, Cy3 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-Factor I light chain
- Long nameFactor I light chain Polyclonal Antibody, Cy3 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy3
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenFactor I light chain
- SpecificityThis is a highly specific antibody against Factor I light chain.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic peptide derived from human Factor I Complement factor I light chain
- Gene ID number3426
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundThe complement pathway is an important host defense system that contributes to both innate and acquired immunity. There are three pathways of complement activation: the classical pathway, lectin pathway and alternative pathway. Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases. It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It requires protein cofactors for cleavage of these complement proteins; Factor H, CR1 or MCP are required for C3b cleavage, and C4bp or CR1 are required for C4b cleavage.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission512,550nm/570,615nm
- SynonymsFactor I light chain; AHUS3; C3b INA; C3b inactivator; C3B/C4B inactivator; C3BINA; CFAI_HUMAN; CFI; Complement component I; Complement control protein factor I; Complement factor I; Complement factor I light chain; F1; factor I; FactorI; FI; I factor; ; KAF; Konglutinogen activating factor; Light chain of factor I; OTTHUMP00000219728.
- Gene targetFactor I light chain Conjugated
- isotype filter
- Immunoglobulin G IgG
- LabelCy3
- label filter
- Cy3
- technique filter
- Antibody
- light
- TechniqueAntibody, light, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies