- Catalog numberbs-11643R-Cy5.5
- Product nameCLACP/COL25A1 Antibody, Cy5.5 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-CLACP/COL25A1
- Long nameCLACP/COL25A1 Polyclonal Antibody, Cy5.5 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy5.5
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenCLACP/COL25A1
- SpecificityThis is a highly specific antibody against CLACP/COL25A1.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Subcellular locationExtracellular
- SourceKLH conjugated synthetic peptide derived from human CLACP/COL25A1
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundCollagen proteins (products of the COL gene family) are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. The Collagen Type XXV precursor produces the proteolytic fragment CLAC (collagenous Alzheimer amyloid plaque component), which deposits in senile plaques associated with amyloid beta peptides (Abeta) in the brains of patients with Alzheimer's disease. CLAC binds to the fibrillized form of Abeta, which disturbs the structure and function of plasma membranes.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission675nm/694nm
- SynonymsAlzheimer disease amyloid associated protein; AMY; CLAC; CLAC P; CLAC precursor; COL25A1; COL25A1 protein; Collagen alpha 1 XXV chain; Collagen alpha 1XXV chain; Collagen like Alzheimer amyloid plaque component; Collagen like Alzheimer amyloid plaque component precursor; Collagen type XXV alpha 1; Collagenous Alzheimer amyloid plaque component.
- Gene targetCLACP/COL25A1 Conjugated
- Identity:HGNC:18603
- Gene:COL25A1
- Long gene name:collagen type XXV alpha 1 chain
- Synonyms gene name:collagen, type XXV, alpha 1
- Discovery year:2003-04-10
- Entrez gene record:84570
- Pubmed identification:11927537
- RefSeq identity:NM_032518
- Classification:Collagens
- VEGA ID:OTTHUMG00000150039
- Identity:HGNC:32963
- Gene:COL25A1-DT
- Long gene name:COL25A1 divergent transcript
- Synonyms gene name:zinc finger CCHC-type containing 23
- Synonyms:FLJ45231
- Discovery year:2006-07-14
- Entrez gene record:645078
- RefSeq identity:NR_160939
- Classification:Divergent transcripts
- Gene symbolCOL25A1, COL25A1-DT
- isotype filter
- Immunoglobulin G IgG
- LabelCy5.5
- label filter
- Cy5.5
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies