- Catalog numberbs-10599R-Cy5
- Product nameCD45 Antibody, Cy5 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-CD45
- Long nameCD45 Polyclonal Antibody, Cy5 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy5
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenCD45
- SpecificityThis is a highly specific antibody against CD45.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range500-530/1291
- Subcellular locationExtracellular
- SourceKLH conjugated synthetic peptide derived from mouse CD45
- Swiss ProtP06800
- Tested applicationsFCM
- Recommended dilutionsFCM(1:20-100)
- CrossreactivityMouse
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundProtein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission625,650nm/670nm
- SynonymsReceptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, Lymphocyte antigen 5, L-CA, Ly-5, T200
- Gene targetCD45 Conjugated
- Identity:HGNC:9666
- Gene:PTPRC
- Long gene name:protein tyrosine phosphatase receptor type C
- Synonyms:LCAT200GP180
- Discovery year:1986-01-01
- Entrez gene record:5788
- Pubmed identification:2169617
- RefSeq identity:NM_002838
- Classification:Protein tyrosine phosphatases receptor type, Fibronectin type III domain containing, CD molecules
- VEGA ID:OTTHUMG00000035702
- Gene symbolPTPRCAP, PTPRC
- isotype filter
- Immunoglobulin G IgG
- LabelCy5
- label filter
- Cy5
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies
Gene info
Gene info
Locus Specific Databases:PTPRCbase: Mutation registry for CD45 deficiencyLRG_95