- Catalog numberbs-0081R-PE
- Product nameCaspase 3 Antibody, PE Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-Caspase-3
- Long nameCaspase 3 Polyclonal Antibody, PE Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationPE
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenCaspase-3
- SpecificityThis is a highly specific antibody against Caspase-3.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range60-100/277
- Subcellular locationCytoplasm
- SourceKLH conjugated synthetic peptide derived from human Caspase 3(Active)
- Gene ID number836
- Swiss ProtP42574
- Tested applicationsFCM
- Recommended dilutionsFCM(1:20-100)
- CrossreactivityHuman, Mouse, Rat, Bovine, Goat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission480,565nm/578nm
- SynonymsCPP32; SCA-1; CPP32B; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; CASP3
- Gene targetCaspase 3 PE Conjugated
- isotype filter
- Immunoglobulin G IgG
- LabelPE
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- PE
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- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies