- Catalog numberbs-7083R-Cy5.5
- Product nameCARD14 Antibody, Cy5.5 Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-CARD14
- Long nameCARD14 Polyclonal Antibody, Cy5.5 Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationCy5.5
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenCARD14
- SpecificityThis is a highly specific antibody against CARD14.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic peptide derived from human CARD14
- Gene ID number79092
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundThe protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission675nm/694nm
- SynonymsBcl10 interacting MAGUK protein 2; Bimp 2; Bimp2; CARD 14; CARD containing MAGUK 2 protein; CARD containing MAGUK protein 2; Card maguk protein 2; Carma 2; Carma2; Caspase recruitment domain containing protein 14; Caspase recruitment domain family member 14; Caspase recruitment domain protein 14; CAR14_HUMAN.
- Alternative to gene target
- [ "caspase recruitment domain family, member 14", "CARD14 and IDBG-71483 and ENSG00000141527 and 79092", "CARD domain binding", "Plasma membranes", "Card14 and IDBG-214692 and ENSMUSG00000013483 and 170720", "CARD14 and IDBG-642674 and ENSBTAG00000015261 and 523360" ]
- Gene targetCARD14 Conjugated
- Identity:HGNC:16446
- Gene:CARD14
- Long gene name:caspase recruitment domain family member 14
- Synonyms gene name:psoriasis susceptibility 2, caspase recruitment domain family, member 14
- Synonyms:CARMA2, BIMP2
- Discovery year:2002-09-19
- Entrez gene record:79092
- Pubmed identification:11278692, 11356195, 22521418
- Classification:Membrane associated guanylate kinases, PDZ domain containing, Caspase recruitment domain containing
- VEGA ID:OTTHUMG00000177549
- Gene symbolCARD14
- isotype filter
- Immunoglobulin G IgG
- LabelCy5.5
- label filter
- Cy5.5
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:LRG_1330