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ASK1 (Ser966) Antibody, Cy5.5 Conjugated

  • Catalog number
    bs-3007R-Cy5.5
  • Product name
    ASK1 (Ser966) Antibody, Cy5.5 Conjugated
  • Size
    0.1ml
  • Short name
    Anti-ASK1 Ser966
  • Long name
    ASK1 (Ser966) Polyclonal Antibody, Cy5.5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy5.5
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    ASK1 Ser966
  • Specificity
    This is a highly specific antibody against ASK1 Ser966.
  • Modification
    Phosphorylation
  • Modification site
    Ser966
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Subcellular location
    Cytoplasm
  • Source
    KLH conjugated synthetic phosphopeptide derived from human ASK1 around the phosphorylation site of Ser966
  • Gene ID number
    4217
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    675nm/694nm
  • Synonyms
    ASK1 phospho S966; p-ASK1 phospho S966; ASK1Ser966; Mitogen-activated protein kinase kinase kinase 5; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; Apoptosis signal-regulating kinase 1; ASK-1; MAP3K5; ASK1; MAPKKK5; MEKK5; M3K5_HUMAN.
  • Gene target
    ASK1 Ser966 Conjugated
    • Gene info
    • Identity:HGNC:6857
    • Gene:MAP3K5
    • Long gene name:mitogen-activated protein kinase kinase kinase 5
    • Synonyms:MAPKKK5ASK1
    • Discovery year:1997-11-14
    • Entrez gene record:4217
    • Pubmed identification:9465908
    • Classification:Mitogen-activated protein kinase kinase kinases
    • VEGA ID:OTTHUMG00000015647
    Locus Specific Databases:The Globin Gene Server
  • Gene symbol
    MAP3K5
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    Cy5.5
  • label filter
    • Cy5.5
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies