- Catalog numberbs-10115R-A647
- Product nameTau protein(Ser733) Antibody, ALEXA FLUOR 647
- Size100ul
- PriceAsk For Price
- Short nameAnti-Tau protein Ser733
- Long nameTau protein(Ser733) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
- Also known asAnti-Tau protein Ser733 PAb ALEXA FLUOR 647
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 647
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenTau protein Ser733
- SpecificityThis is a highly specific antibody against Tau protein Ser733.
- ModificationPhosphorylation
- Modification SiteSer733
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser733
- Gene ID Number4137
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenTau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission650nm/665nm
- SynonymsMAPTphospho S733; p-Tau protein Ser733; MAPT; Microtuble-associted protein Tau; AI413597; AW045860; DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FLJ31424; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PHF-tau; PPND; pTau; RNPTAU; Tauopathy and respiratory failure, included; TAU_HUMAN.
- Gene targetTau protein Ser733
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 647
- label filter
- ALEXA FLUOR 647
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies