- Catalog numberbs-5669R-A350
- Product nameRPS6KB1(Thr 412) Antibody, ALEXA FLUOR 350
- Size100ul
- PriceAsk For Price
- Short nameAnti-RPS6KB1 Thr 412
- Long nameRPS6KB1(Thr 412) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
- Also known asAnti-RPS6KB1 Thr 412 PAb ALEXA FLUOR 350
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 350
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenRPS6KB1 Thr 412
- SpecificityThis is a highly specific antibody against RPS6KB1 Thr 412.
- ModificationPhosphorylation
- Modification SiteThr 412
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic phosphopeptide derived from human RPS6KB1 around the phosphorylation site of Thr412
- Gene ID Number6198
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenThis gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission343nm/442nm
- SynonymsRPS6KB1 phospho S412; RPS6KB1 phospho Ser412; p-RPS6KB1 Ser412; RPS6KB1; PS6K; S6K; S6K1; STK14A; p70S6K-alpha; p70-S6K; p70-alpha; ribosomal protein S6 kinase; 70kDa; p70 S6 Kinase; P70 Beta1; KS6B1_HUMAN; Ribosomal protein S6 kinase beta-1; S6K-beta-1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA.
- Alternative to gene target
- [ "ribosomal protein S6 kinase, 70kDa, polypeptide 1", "p70 S6KA and p70-alpha and p70-S6K and p70(S6K)-alpha and PS6K and S6K and S6K-beta-1 and S6K1 and STK14A", "RPS6KB1 and IDBG-61938 and ENSG00000108443 and 6198", "transferase activity", "nuclei", "Rps6kb1 and IDBG-206895 and ENSMUSG00000020516 and 72508", "RPS6KB1 and IDBG-629797 and ENSBTAG00000016851 and 404181" ]
- Gene targetRPS6KB1 Thr 412
- Identity:HGNC:10436
- Gene:RPS6KB1
- Long gene name:ribosomal protein S6 kinase B1
- Synonyms gene name:ribosomal protein S6 kinase, 70kD, polypeptide 1
- Synonyms:S6K1p70(S6K)-alphaPS6KS6K
- Discovery year:1994-07-11
- Entrez gene record:6198
- Pubmed identification:1922062
- RefSeq identity:NM_003161
- Classification:AGC family kinases
- VEGA ID:OTTHUMG00000150642
- Gene symbolRPS6KB1
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 350
- label filter
- ALEXA FLUOR 350
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies