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RanBP3 Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-20113R-A555
  • Product name
    RanBP3 Antibody, ALEXA FLUOR 555
  • Size
    100ul
  • Short name
    Anti-RanBP3
  • Long name
    RanBP3 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-RanBP3 PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    RanBP3
  • Specificity
    This is a highly specific antibody against RanBP3.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    450-500/567
  • Subcellular location
    Cytoplasm, Nucleus
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RanBP3
  • Gene ID Number
    8498
  • Swiss Prot
    Q9H6Z4
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    Ran-binding protein 3; RanBP3
  • Gene target
    RanBP3
    • Gene info
    • Identity:HGNC:55312
    • Gene:RANBP3-DT
    • Long gene name:RANBP3 divergent transcript
    • Discovery year:2020-10-19
    • Entrez gene record:100128568
    • RefSeq identity:NR_046376
    • Classification:Divergent transcripts
    Gene info
  • Gene symbol
    RANBP3-DT, RANBP3
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 555
  • label filter
    • ALEXA FLUOR 555
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies