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PRKCA(Ser657+Tyr658) Antibody, ALEXA FLUOR 350

  • Catalog number
    bs-5573R-A350
  • Product name
    PRKCA(Ser657+Tyr658) Antibody, ALEXA FLUOR 350
  • Size
    100ul
  • Short name
    Anti-PRKCA Ser657+Tyr658
  • Long name
    PRKCA(Ser657+Tyr658) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
  • Also known as
    Anti-PRKCA Ser657+Tyr658 PAb ALEXA FLUOR 350
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 350
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    PRKCA Ser657+Tyr658
  • Specificity
    This is a highly specific antibody against PRKCA Ser657+Tyr658.
  • Modification
    Phosphorylation
  • Modification Site
    Ser657+Tyr658
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic phosphopeptide derived from human PRKCA around the phosphorylation site of Ser657+Tyr658
  • Gene ID Number
    5578
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    343nm/442nm
  • Synonyms
    PRKCAphospho S657/Y658; rotein Kinase C; AAG6; Aging associated gene 6; MGC129900; MGC129901; MGC41878; MGC57564; PKC B; PKC beta; PKC zeta; PKC2; PKCB; PKCC; PKCD; PKCE; PKCG; PRKACA; PRKC A; PRKC G; PRKCA; PRKCB; PRKCB1; PRKCB2; PRKCD; PRKCE; PRKCG; PRKCZ ; Protein kinase C alpha; Protein kinase C alpha type; Protein Kinase C; Protein kinase C beta 1; Protein kinase C beta 1 polypeptide; Protein kinase C beta; Protein kinase C beta type; Protein kinase C delta; Protein kinase C epsilon; Protein kinase C gamma; Protein kinase C gamma type; Protein kinase C zeta; SCA14; Spinocerebellar ataxia 14.
  • Alternative to gene target
    • [ "protein kinase C, alpha", "AAG6 and PKC-alpha and PKCA and PRKACA", "PRKCA and IDBG-65194 and ENSG00000154229 and 5578", "transferase activity", "nuclei", "Prkca and IDBG-213736 and ENSMUSG00000050965 and 18750", "BT.62458 and IDBG-643753 and ENSBTAG00000001061 and 282001" ]
  • Gene target
    PRKCA Ser657+Tyr658
    • Gene info
    Gene info
  • Gene symbol
    PRKCA-AS1, PRKCA
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 350
  • label filter
    • ALEXA FLUOR 350
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies