- Catalog numberbs-7340R-A488
- Product namePRG2 Antibody, ALEXA FLUOR 488
- Size100ul
- PriceAsk For Price
- Short nameAnti-PRG2
- Long namePRG2 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
- Also known asAnti-PRG2 PAb ALEXA FLUOR 488
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 488
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenPRG2
- SpecificityThis is a highly specific antibody against PRG2.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRG2
- Gene ID Number5553
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenThe protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission499nm/519nm
- SynonymsBMPG; EMBP; Eosinophil granule major basic protein; Eosinophil major basic protein; MBP; MBP1; Natural killer cell activator; Pregnancy-associated major basic protein; PRG 2; PRG2; PRG2_HUMAN; Proteoglycan 2; Proteoglycan 2 bone marrow; Proteoglycan 2 preproprotein.
- Alternative to gene target
- [ "proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)", "BMPG and MBP and MBP1", "PRG2 and IDBG-46552 and ENSG00000186652 and 5553", "carbohydrate binding", "Extracellular", "Prg2 and IDBG-185619 and ENSMUSG00000027073 and 19074" ]
- Gene targetPRG2
- Identity:HGNC:9362
- Gene:PRG2
- Long gene name:proteoglycan 2, pro eosinophil major basic protein
- Synonyms gene name:proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
- Synonyms:MBPBMPGproMBP
- Discovery year:1993-09-29
- Entrez gene record:5553
- Pubmed identification:1565101
- RefSeq identity:NM_002728
- Classification:C-type lectin domain containing
- VEGA ID:OTTHUMG00000167027
- Identity:HGNC:23497
- Gene:PLPPR3
- Long gene name:phospholipid phosphatase related 3
- Synonyms:PRG-2FLJ11535LPPR3PRG2
- Discovery year:2015-10-14
- Entrez gene record:79948
- Pubmed identification:12730698
- RefSeq identity:NM_024888
- Classification:Phospholipid phosphatase related
- VEGA ID:OTTHUMG00000164523
- Identity:HGNC:14966
- Gene:PXDN
- Long gene name:peroxidasin
- Synonyms gene name:peroxidasin homolog (Drosophila)
- Synonyms:KIAA0230PRG2MG50D2S448D2S448EPXN
- Discovery year:2005-07-19
- Entrez gene record:7837
- Pubmed identification:10441517, 9039502, 22842973
- RefSeq identity:NM_012293
- Classification:I-set domain containing
- VEGA ID:OTTHUMG00000059697
- Gene symbolPRG2, PLPPR3, PXDN
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 488
- label filter
- ALEXA FLUOR 488
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies