- Catalog numberbs-5509R-A555
- Product nameNFKB1 (Ser903) Antibody, ALEXA FLUOR 555
- Size100ul
- PriceAsk For Price
- Short nameAnti-NFKB1 Ser903
- Long nameNFKB1 (Ser903) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
- Also known asAnti-NFKB1 Ser903 PAb ALEXA FLUOR 555
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 555
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenNFKB1 Ser903
- SpecificityThis is a highly specific antibody against NFKB1 Ser903.
- ModificationPhosphorylation
- Modification SiteSer903
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic phosphopeptide derived from human NF KappaB p105 around the phosphorylation site of Ser903 [AH(p-S)LP]
- Gene ID Number4790
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. SUBUNIT: Active NF-kappa-B is a heterodimer of an about 50 kDa DNA-binding subunit and the weak DNA-binding subunit p65. Two heterodimers might form a labile tetramer. Also interacts with MAP3K8. NF-kappa-B p50 subunit interacts with NCOA3 coactivator, which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI; this interaction prevents nuclear translocation and DNA-binding. Interacts with SPAG9 and UNC5CL.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission553nm/568nm
- SynonymsDKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; NF kappa B; NF kappabeta; NF kB1; NFKB 1; NFKB p105; NFKB p50; NFKB1; NFKB1_HUMAN; Nuclear factor kappa B DNA binding subunit; Nuclear factor NF kappa B p105 subunit; Nuclear factor NF kappa B p50 subunit; Nuclear factor NF-kappa-B p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p84/NF-kappa-B1 p98.
- Alternative to gene target
- [ "nuclear factor of kappa light polypeptide gene enhancer in B-cells 1", "EBP-1 and KBF1 and NF-kappa-B and NF-kappaB and NF-kB1 and NFkappaB and NFKB-p105 and NFKB-p50 and p105 and p50", "NFKB1 and IDBG-31974 and ENSG00000109320 and 4790", "transcription regulatory region DNA binding", "nuclei", "Nfkb1 and IDBG-195445 and ENSMUSG00000028163 and 18033", "BT.60919 and IDBG-640840 and ENSBTAG00000020270 and 616115" ]
- Gene targetNFKB1 Ser903
- Identity:HGNC:7794
- Gene:NFKB1
- Long gene name:nuclear factor kappa B subunit 1
- Synonyms gene name:nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- Synonyms:KBF1p105NFKB-p50p50NF-kappaBNFkappaBNF-kB1
- Discovery year:1991-11-14
- Entrez gene record:4790
- Pubmed identification:1992489
- RefSeq identity:NM_003998
- Classification:NF-kappa B complex subunits, Ankyrin repeat domain containing, IPT domain containing
- VEGA ID:OTTHUMG00000161080
- Gene symbolNFKB1
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 555
- label filter
- ALEXA FLUOR 555
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:LRG_1316