- Catalog numberbs-15541R-A350
- Product nameIDN3 Antibody, ALEXA FLUOR 350
- Size100ul
- PriceAsk For Price
- Short nameAnti-IDN3
- Long nameIDN3 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
- Also known asAnti-IDN3 PAb ALEXA FLUOR 350
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 350
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenIDN3
- SpecificityThis is a highly specific antibody against IDN3.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IDN3
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenThis gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission343nm/442nm
- SynonymsCDLS; Colon tumor susceptibility 2; Delangin; DKFZp434L1319; FLJ11203; FLJ12597; FLJ13354; FLJ13648; FLJ44854; IDN 3; IDN 3 protein; IDN 3 protein isoform A; IDN 3 protein isoform B; IDN 3B; IDN3 B; IDN3 protein; IDN3 protein isoform A; IDN3 protein isoform B; IDN3B; Mis 4; Mis4; Nipbl; NIPBL_HUMAN; Nipped B homolog Drosophila; Nipped B homolog; Nipped B like; Nipped B like protein; Nipped-B-like protein; Scc 2; SCC 2 homolog; Scc2; SCC2 homolog; Sister chromatid cohesion protein Mis4.
- Gene targetIDN3
- Identity:HGNC:28862
- Gene:NIPBL
- Long gene name:NIPBL cohesin loading factor
- Synonyms gene name:Nipped-B homolog (Drosophila), NIPBL, cohesin loading factor
- Synonyms:IDN3, DKFZp434L1319FLJ11203FLJ12597FLJ13354FLJ13648Scc2
- Discovery year:2004-07-21
- Entrez gene record:25836
- Pubmed identification:15146186, 15146185
- RefSeq identity:NM_015384
- Classification:Armadillo like helical domain containing
- VEGA ID:OTTHUMG00000090795
- Gene symbolNIPBL
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 350
- label filter
- ALEXA FLUOR 350
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:LOVDGlobal Variome shared LOVD