• Catalog number
    bs-10463R-A350
  • Product name
    HEXB chain A Antibody, ALEXA FLUOR 350
  • Size
    100ul
  • Short name
    Anti-HEXB chain A
  • Long name
    HEXB chain A Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
  • Also known as
    Anti-HEXB chain A PAb ALEXA FLUOR 350
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 350
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    HEXB chain A
  • Specificity
    This is a highly specific antibody against HEXB chain A.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HEXB chain A
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008].
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    343nm/442nm
  • Synonyms
    Beta hexosaminidase beta chain; Beta hexosaminidase subunit beta; Beta N acetylhexosaminidase; Beta-hexosaminidase subunit beta chain A; Beta-N-acetylhexosaminidase subunit beta; Cervical cancer proto oncogene 7 protein; Cervical cancer proto-oncogene 7 protein; ENC 1AS; HCC 7; HCC-7; HCC7; HEX B; Hexb; HEXB_HUMAN; Hexosaminidase B beta polypeptide; Hexosaminidase B; Hexosaminidase subunit B; HexosaminidaseB; N acetyl beta glucosaminidase; N-acetyl-beta-glucosaminidase subunit beta; HEXB chain A.
  • Gene target
    HEXB chain A
  • Gene info
  • Gene symbol
    HEXB
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 350
  • label filter
    • ALEXA FLUOR 350
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies