- Catalog numberbs-10463R-A350
- Product nameHEXB chain A Antibody, ALEXA FLUOR 350
- Size100ul
- PriceAsk For Price
- Short nameAnti-HEXB chain A
- Long nameHEXB chain A Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
- Also known asAnti-HEXB chain A PAb ALEXA FLUOR 350
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 350
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenHEXB chain A
- SpecificityThis is a highly specific antibody against HEXB chain A.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HEXB chain A
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenHexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008].
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission343nm/442nm
- SynonymsBeta hexosaminidase beta chain; Beta hexosaminidase subunit beta; Beta N acetylhexosaminidase; Beta-hexosaminidase subunit beta chain A; Beta-N-acetylhexosaminidase subunit beta; Cervical cancer proto oncogene 7 protein; Cervical cancer proto-oncogene 7 protein; ENC 1AS; HCC 7; HCC-7; HCC7; HEX B; Hexb; HEXB_HUMAN; Hexosaminidase B beta polypeptide; Hexosaminidase B; Hexosaminidase subunit B; HexosaminidaseB; N acetyl beta glucosaminidase; N-acetyl-beta-glucosaminidase subunit beta; HEXB chain A.
- Gene targetHEXB chain A
- Identity:HGNC:4879
- Gene:HEXB
- Long gene name:hexosaminidase subunit beta
- Synonyms gene name:hexosaminidase B (beta polypeptide)
- Discovery year:2001-06-22
- Entrez gene record:3074
- Pubmed identification:2579389, 3013851
- RefSeq identity:NM_000521
- Classification:Hexosaminidases
- VEGA ID:OTTHUMG00000102057
- Gene symbolHEXB
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 350
- label filter
- ALEXA FLUOR 350
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:HEXB Locus Database