- Catalog numberbs-11291R-A555
- Product nameHDC2/PHC2 Antibody, ALEXA FLUOR 555
- Size100ul
- PriceAsk For Price
- Short nameAnti-HDC2/PHC2
- Long nameHDC2/PHC2 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
- Also known asAnti-HDC2/PHC2 PAb ALEXA FLUOR 555
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 555
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenHDC2/PHC2
- SpecificityThis is a highly specific antibody against HDC2/PHC2.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HDC2/PHC2
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenEarly development regulatory protein 2;hPH2;early development regulator 2 (homolog of polyhomeotic 2);Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development. PHC2 (polyhomeotic-like protein 2), also known as early development regulatory protein 2, is an 858 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Phosphorylated upon DNA damage, PHC2 contains one SAM (sterile alpha motif) domain and one FCS-type zinc finger.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission553nm/568nm
- SynonymsEarly development regulatory protein 2; hPH2; early development regulator 2 homolog of polyhomeotic 2; early development regulator 2 like; EDR2; MGC163502; mph2; PH2; PHC2; PHC2_HUMAN; polyhomeotic 2; polyhomeotic like 2; Polyhomeotic-like protein 2.
- Gene targetHDC2/PHC2
- Identity:HGNC:40205
- Gene:PHC2-AS1
- Long gene name:PHC2 antisense RNA 1
- Discovery year:2019-09-19
- Entrez gene record:101929464
- RefSeq identity:NR_125978
- Classification:Antisense RNAs
- Identity:HGNC:3183
- Gene:PHC2
- Long gene name:polyhomeotic homolog 2
- Synonyms gene name:early development regulator 2 (homolog of polyhomeotic 2), polyhomeotic-like 2 (Drosophila), polyhomeotic homolog 2 (Drosophila)
- Synonyms:HPH2,
- Discovery year:1997-09-12
- Entrez gene record:1912
- Pubmed identification:9121482, 12384788
- RefSeq identity:NM_198040
- Classification:Sterile alpha motif domain containing, MicroRNA protein coding host genes
- VEGA ID:OTTHUMG00000004133
- Gene symbolPHC2-AS1, PHC2
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 555
- label filter
- ALEXA FLUOR 555
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies