- Catalog numberbs-15429R-A555
- Product nameHCP5 Antibody, ALEXA FLUOR 555
- Size100ul
- PriceAsk For Price
- Short nameAnti-HCP5
- Long nameHCP5 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
- Also known asAnti-HCP5 PAb ALEXA FLUOR 555
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 555
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenHCP5
- SpecificityThis is a highly specific antibody against HCP5.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HCP5
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenHCP5 is a region present on chromosome 6p21.3 that is characterized by multiple duplicated gene families. HCP5 (HLA class I histocompatibility antigen protein P5), also known as P5-1, is a 132 amino acid protein that is encoded by a gene mapping to human chromosome 6p21.33. Localizing within the MHC class I region, HCP5 is not structurally related to other MHC class I genes, but does have high sequence similarity with HERV-L and HERV-16. HCP5 also has high sequence homology to retroviral Pol genes, making it a possible candidate for interaction with HIV-1 through an antisense mechanism that prevents retrovirus transcription. Single-nucleotide polymorphisms (SNPs) to the region of the HCP5 gene that corresponds with HLA-B has been linked to a lower HIV-1 viral set point. HCP5 is highly expressed in lymphoid tissues, spleen and activated lymphocytes, as well as B-cell and natural killer (NK) cell lines.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission553nm/568nm
- SynonymsHLA class I histocompatibility antigen protein P5; HLA complex protein P5; Protein P5 1; HCP5_HUMAN.
- Alternative to gene target
- [ "HLA complex P5 (non-protein coding)", "6S2650E and D6S2650E and P5-1", "HCP5 and IDBG-126054 and ENSG00000206337 and 10866", "multiple" ]
- Gene targetHCP5
- Identity:HGNC:24416
- Gene:CYCSP5
- Long gene name:CYCS pseudogene 5
- Synonyms gene name:cytochrome c, somatic pseudogene 5
- Synonyms:HCP5
- Discovery year:2005-04-29
- Entrez gene record:360158
- Pubmed identification:12909341, 12815422
- RefSeq identity:NG_002956
- VEGA ID:OTTHUMG00000040399
- Identity:HGNC:21659
- Gene:HCP5
- Long gene name:HLA complex P5
- Synonyms gene name:HLA complex P5, HLA complex P5 (non-protein coding)
- Synonyms:D6S2650E, P5-1
- Discovery year:2003-07-07
- Entrez gene record:10866
- Pubmed identification:8462994, 10199916, 31215169
- RefSeq identity:NR_040662
- Classification:Long non-coding RNAs with non-systematic symbols
- VEGA ID:OTTHUMG00000031282
- Gene symbolCYCSP5, HCP5
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 555
- label filter
- ALEXA FLUOR 555
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies