- Catalog numberbs-10419R-A488
- Product nameGPI Antibody, ALEXA FLUOR 488
- Size100ul
- PriceAsk For Price
- Short nameAnti-GPI
- Long nameGPI Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
- Also known asAnti-GPI PAb ALEXA FLUOR 488
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 488
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenGPI
- SpecificityThis is a highly specific antibody against GPI.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glucose 6 phosphate isomerase
- Gene ID Number51701
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenThis gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. [provided by RefSeq, Jul 2008].
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission499nm/519nm
- SynonymsGlucose 6 phosphate isomerase; AMF; Aurocrine motility factor; Autocrine motility factor; DKFZp686C13233; EC 5.3.1.9; G6PI_HUMAN; Glucose phosphate isomerase; Glucose-6-phosphate isomerase; GNPI; GPI; Gpi1; Hexose monophosphate isomerase; Hexosephosphate isomerase; Neuroleukin; NLK; Oxoisomerase; PHI; Phosphoglucose isomerase; Phosphohexomutase; Phosphohexose isomerase; Phosphosaccharomutase; SA 36; SA-36; SA36; Sperm antigen 36.
- Alternative to gene target
- [ "glucose-6-phosphate isomerase", "AMF and GNPI and NLK and PGI and PHI and SA-36 and SA36", "GPI and IDBG-42902 and ENSG00000105220 and 2821", "monosaccharide binding", "nuclei", "GPI and IDBG-635386 and ENSBTAG00000006396 and 280808" ]
- Gene targetGPI
- Identity:HGNC:4458
- Gene:GPI
- Long gene name:glucose-6-phosphate isomerase
- Synonyms gene name:glucose phosphate isomerase
- Synonyms:AMFNLK
- Discovery year:2001-06-22
- Entrez gene record:2821
- Pubmed identification:2387591, 8575767
- VEGA ID:OTTHUMG00000182087
- Identity:HGNC:8964
- Gene:PIGH
- Long gene name:phosphatidylinositol glycan anchor biosynthesis class H
- Synonyms gene name:phosphatidylinositol glycan, class H
- Synonyms:GPI-H
- Discovery year:1994-09-06
- Entrez gene record:5283
- Pubmed identification:8204896
- RefSeq identity:NM_004569
- Classification:Phosphatidylinositol glycan anchor biosynthesis
- VEGA ID:OTTHUMG00000171806
- Identity:HGNC:18858
- Gene:PIGM
- Long gene name:phosphatidylinositol glycan anchor biosynthesis class M
- Synonyms gene name:phosphatidylinositol glycan, class M
- Synonyms:GPI-MT-I
- Discovery year:2002-07-05
- Entrez gene record:93183
- Pubmed identification:11226175
- RefSeq identity:NM_145167
- Classification:Dolichyl D-mannosyl phosphate dependent mannosyltransferases, Phosphatidylinositol glycan anchor biosynthesis
- VEGA ID:OTTHUMG00000024081
- Identity:HGNC:24945
- Gene:GPIHBP1
- Long gene name:glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
- Synonyms gene name:GPI anchored high density lipoprotein binding protein 1
- Synonyms:LOC338328GPI-HBP1
- Discovery year:2008-02-07
- Entrez gene record:338328
- Pubmed identification:12496272, 17883852, 17620854, 17403372
- RefSeq identity:NM_178172
- Classification:LY6/PLAUR domain containing
- VEGA ID:OTTHUMG00000164950
- Identity:HGNC:12706
- Gene:VNN2
- Long gene name:vanin 2
- Synonyms:FOAP-4GPI-80
- Discovery year:1998-11-13
- Entrez gene record:8875
- Pubmed identification:9790769, 11491533
- Classification:Vanin family
- VEGA ID:OTTHUMG00000015588
- Gene symbolGPI, PIGH, PIGM, GPIHBP1, VNN2, GNPDA1
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 488
- label filter
- ALEXA FLUOR 488
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:LRG_1178