- Catalog numberbs-10458R-A647
- Product nameGGT5 light chain Antibody, ALEXA FLUOR 647
- Size100ul
- PriceAsk For Price
- Short nameAnti-GGT5 light chain
- Long nameGGT5 light chain Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
- Also known asAnti-GGT5 light chain PAb ALEXA FLUOR 647
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 647
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenGGT5 light chain
- SpecificityThis is a highly specific antibody against GGT5 light chain.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Subcellular locationExtracellular
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 light chain
- Tested applicationsFCM, IF(IHC-P)
- Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigeng-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in some liver diseases. GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma. GGT5 converts Leukotriene C4 to Leukotriene D4; it does not, however, convert synthetic substrates that are commonly used to assay GGT. In human serum and tissues there is a marked heterogeneity in GGT, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission650nm/665nm
- SynonymsGamma glutamyl transpeptidase related enzyme; Gamma glutamyltranspeptidase 5; Gamma-glutamyl transpeptidase-related enzyme; Gamma-glutamyltransferase 5 heavy chain; Gamma-glutamyltransferase-like activity 1; Gamma-glutamyltranspeptidase 5; GGT 5; GGT REL; GGT-rel; GGT5; GGT5_HUMAN; DKFZP566O011; GGTLA1; Glutathione hydrolase 5; Leukotriene-C4 hydrolase; Gamma-glutamyltransferase 5 light chain.
- Gene targetGGT5 light chain
- Identity:HGNC:4260
- Gene:GGT5
- Long gene name:gamma-glutamyltransferase 5
- Synonyms gene name:gamma-glutamyltransferase-like activity 1
- Synonyms:GGT-REL
- Discovery year:1992-08-24
- Entrez gene record:2687
- Pubmed identification:1676842, 8095916, 18357469
- RefSeq identity:NM_004121
- Classification:Gamma-glutamyltransferases
- VEGA ID:OTTHUMG00000150796
- Gene symbolGGT5
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 647
- label filter
- ALEXA FLUOR 647
- technique filter
- Antibody
- light
- TechniqueAntibody, light, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies