- Catalog numberbs-13276R-A647
- Product namegamma Crystallin Antibody, ALEXA FLUOR 647
- Size100ul
- PriceAsk For Price
- Short nameAnti-gamma Crystallin
- Long namegamma Crystallin Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
- Also known asAnti-gamma Crystallin PAb ALEXA FLUOR 647
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 647
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target Antigengamma Crystallin
- SpecificityThis is a highly specific antibody against gamma Crystallin.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range120-170/174
- Subcellular locationCytoplasm, Nucleus
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human gamma C Crystallin/CRYG3
- Gene ID Number1420, 1419, 1418, 1421, 1422
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenCrystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into alpha, beta, and gamma families, and the beta and gamma-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. gamma-crystallins are structural proteins in the lens, and they exists as monomers which typically lack connecting peptides and terminal extensions. The gamma-crystallins include seven closely related gamma A, gamma B, gamma C, gamma D, gamma E, gamma F, and gamma G-crystallin, as well as the gamma N and gamma S-crystallin genes. The gamma-crystallins are differentially regulated after early development, and are involved in cataract formation as a result of either age-related protein degradation or genetic mutation.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission650nm/665nm
- SynonymsCRYG3; CRYG1; CRYG2; CRYG4; CRYG5;Gamma-crystallin 5; Gamma-crystallin 4; Gamma-crystallin 1; Gamma-crystallin 2; Gamma-crystallin 3.
- Gene targetgamma Crystallin
- Identity:HGNC:2409
- Gene:CRYGB
- Long gene name:crystallin gamma B
- Synonyms gene name:crystallin, gamma 1-2, crystallin, gamma B
- Discovery year:1986-01-01
- Entrez gene record:1419
- RefSeq identity:NM_005210
- Classification:Beta-gamma crystallins
- VEGA ID:OTTHUMG00000132941
- Identity:HGNC:2417
- Gene:CRYGS
- Long gene name:crystallin gamma S
- Synonyms gene name:crystallin, gamma S
- Discovery year:1989-05-25
- Entrez gene record:1427
- RefSeq identity:NM_017541
- Classification:Beta-gamma crystallins
- VEGA ID:OTTHUMG00000156615
- Identity:HGNC:20458
- Gene:CRYGN
- Long gene name:crystallin gamma N
- Synonyms gene name:crystallin, gamma N
- Discovery year:2003-02-25
- Entrez gene record:155051
- Classification:MicroRNA protein coding host genes, Beta-gamma crystallins
- VEGA ID:OTTHUMG00000157353
- Gene symbolCRYGB, CRYGS, CRYGN
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 647
- label filter
- ALEXA FLUOR 647
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Gene info
Locus Specific Databases:Global Variome shared LOVD