- Catalog numberbs-11456R-A594
- Product nameDscam Antibody, ALEXA FLUOR 594
- Size100ul
- PriceAsk For Price
- Short nameAnti-Dscam
- Long nameDscam Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
- Also known asAnti-Dscam PAb ALEXA FLUOR 594
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 594
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenDscam
- SpecificityThis is a highly specific antibody against Dscam.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range280-330/2012
- Subcellular locationExtracellular
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dscam
- Gene ID Number1826
- Swiss ProtO60469
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenCell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding. Enhances netrin-induced phosphorylation of PAK1 and FYN. Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission590nm/617nm
- SynonymsCHD2; CHD2-42; CHD2-52; Down syndrome cell adhesion molecule; DSCAM
- Alternative to gene target
- [ "Down syndrome cell adhesion molecule", "CHD2 and CHD2-42 and CHD2-52", "DSCAM and IDBG-3815 and ENSG00000171587 and 1826", "protein binding", "Extracellular", "Dscam and IDBG-180173 and ENSMUSG00000050272 and 13508", "DSCAM and IDBG-639205 and ENSBTAG00000004754 and 100337016,101908463" ]
- Gene targetDscam
- Identity:HGNC:41327
- Gene:DSCAM-IT1
- Long gene name:DSCAM intronic transcript 1
- Synonyms gene name:DSCAM intronic transcript 1 (non-protein coding)
- Discovery year:2011-05-20
- Classification:Intronic transcripts
- VEGA ID:OTTHUMG00000086730
- Identity:HGNC:40197
- Gene:DSCAM-AS1
- Long gene name:DSCAM antisense RNA 1
- Synonyms gene name:DSCAM antisense RNA 1 (non-protein coding)
- Synonyms:M41
- Discovery year:2011-05-20
- Entrez gene record:100506492
- Pubmed identification:27666543
- RefSeq identity:NR_038896
- Classification:Antisense RNAs
- VEGA ID:OTTHUMG00000086733
- Identity:HGNC:3039
- Gene:DSCAM
- Long gene name:DS cell adhesion molecule
- Synonyms gene name:Down syndrome cell adhesion molecule
- Synonyms:CHD2-42CHD2-52
- Discovery year:1998-06-10
- Entrez gene record:1826
- Pubmed identification:9426258
- RefSeq identity:NM_001389
- Classification:Ig-like cell adhesion molecule family, I-set domain containing, Fibronectin type III domain containing, MicroRNA protein coding host genes
- VEGA ID:OTTHUMG00000086732
- Gene symbolDSCAM-IT1, DSCAM-AS1, DSCAM
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 594
- label filter
- ALEXA FLUOR 594
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies