- Catalog numberbs-13019R-A350
- Product nameDNA Polymerase Kappa/POLK Antibody, ALEXA FLUOR 350
- Size100ul
- PriceAsk For Price
- Short nameAnti-DNA Polymerase Kappa/POLK
- Long nameDNA Polymerase Kappa/POLK Antibody, ALEXA FLUOR 350 Conjugated
- Also known asAnti-DNA Polymerase Kappa/POLK PAb ALEXA FLUOR 350
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 350
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenDNA Polymerase Kappa/POLK
- SpecificityThis is a highly specific antibody against DNA Polymerase Kappa/POLK.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK
- Gene ID Number51426
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenDNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission343nm/442nm
- SynonymsDNA polymerase kappa; DINB protein; Short=DINP; POLK_HUMAN.
- Gene targetDNA Polymerase Kappa/POLK
- Identity:HGNC:9183
- Gene:POLK
- Long gene name:DNA polymerase kappa
- Synonyms gene name:polymerase (DNA directed) kappa, polymerase (DNA) kappa
- Synonyms:POLQ, DINP
- Discovery year:2000-08-11
- Entrez gene record:51426
- Pubmed identification:10887153, 10518552
- RefSeq identity:NM_016218
- Classification:DNA polymerases
- VEGA ID:OTTHUMG00000102107
- Identity:HGNC:9413
- Gene:PRKDC
- Long gene name:protein kinase, DNA-activated, catalytic subunit
- Synonyms gene name:protein kinase, DNA-activated, catalytic polypeptide
- Synonyms:DNPK1p350DNAPKXRCC7DNA-PKcsDNAPKcDNA-PKCp460
- Discovery year:1993-11-09
- Entrez gene record:5591
- Pubmed identification:7638222
- RefSeq identity:NM_001081640
- Classification:Armadillo like helical domain containing
- VEGA ID:OTTHUMG00000164239
- Identity:HGNC:4936
- Gene:HLA-DOA
- Long gene name:major histocompatibility complex, class II, DO alpha
- Synonyms:HLA-D0-alpha
- Discovery year:2001-06-22
- Entrez gene record:3111
- Pubmed identification:2370084
- RefSeq identity:NM_002119
- Classification:C1-set domain containing, Histocompatibility complex
- VEGA ID:OTTHUMG00000031211
- Identity:HGNC:16705
- Gene:TENT4A
- Long gene name:terminal nucleotidyltransferase 4A
- Synonyms gene name:polymerase (DNA directed) sigma, PAP associated domain containing 7, poly(A) RNA polymerase D7, non-canonical
- Synonyms:POLK, TRF4, LAK-1TRF4-1
- Discovery year:2001-09-27
- Entrez gene record:11044
- Pubmed identification:10066793, 10926539, 23376078
- RefSeq identity:NM_006999
- Classification:Terminal nucleotidyltransferases, Non-canonical poly(A) polymerases
- VEGA ID:OTTHUMG00000090457
- Gene symbolPOLK, PRKDC, HLA-DOA, TENT4A
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 350
- label filter
- ALEXA FLUOR 350
- technique filter
- Antibody
- dna
- TechniqueAntibody, dna, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Gene info
Locus Specific Databases:LRG_162
Gene info
Locus Specific Databases:IMGT/HLA Database