- Catalog numberbs-3735R-A350
- Product nameDNA PK/PRKDC(Thr2609) Antibody, ALEXA FLUOR 350
- Size100ul
- PriceAsk For Price
- Short nameAnti-DNA PK/PRKDC Thr2609
- Long nameDNA PK/PRKDC(Thr2609) Antibody, ALEXA FLUOR 350 Conjugated
- Also known asAnti-DNA PK/PRKDC Thr2609 PAb ALEXA FLUOR 350
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 350
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenDNA PK/PRKDC Thr2609
- SpecificityThis is a highly specific antibody against DNA PK/PRKDC Thr2609.
- ModificationPhosphorylation
- Modification SiteThr2609
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic phosphopeptide derived from human PRKDC around the phosphorylation site of Thr2609
- Gene ID Number5591
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenDNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission343nm/442nm
- SynonymsDNA PKcsThr2609; PRKDCphospho T2609; DNA PKcs phospho T2609; p-DNA PKcs phospho T2609; DNA-dependent protein kinase catalytic subunit; DNA-PK catalytic subunit; DNA-PKcs; DNPK1; p460; PRKDC; HYRC; HYRC1; Variant; DNAPK; DNAPK catalytic subunit; p350; PRKDC; Protein Kinase DNA Activated Catalytic Polypeptide; XRCC 7; XRCC7; PRKDC_HUMAN.
- Alternative to gene target
- [ "protein kinase, DNA-activated, catalytic polypeptide", "DNA-PKcs and DNAPK and DNPK1 and HYRC and HYRC1 and IMD26 and p350 and XRCC7", "PRKDC and IDBG-408612 and ENSG00000253729 and 5591", "transferase activity", "nuclei", "Prkdc and IDBG-135771 and ENSMUSG00000022672 and 19090", "PRKDC and IDBG-644289 and ENSBTAG00000017019 and 512740" ]
- Gene targetDNA PK/PRKDC Thr2609
- Identity:HGNC:9413
- Gene:PRKDC
- Long gene name:protein kinase, DNA-activated, catalytic subunit
- Synonyms gene name:protein kinase, DNA-activated, catalytic polypeptide
- Synonyms:DNPK1p350DNAPKXRCC7DNA-PKcsDNAPKcDNA-PKCp460
- Discovery year:1993-11-09
- Entrez gene record:5591
- Pubmed identification:7638222
- RefSeq identity:NM_001081640
- Classification:Armadillo like helical domain containing
- VEGA ID:OTTHUMG00000164239
- Identity:HGNC:4936
- Gene:HLA-DOA
- Long gene name:major histocompatibility complex, class II, DO alpha
- Synonyms:HLA-D0-alpha
- Discovery year:2001-06-22
- Entrez gene record:3111
- Pubmed identification:2370084
- RefSeq identity:NM_002119
- Classification:C1-set domain containing, Histocompatibility complex
- VEGA ID:OTTHUMG00000031211
- Gene symbolPRKDC, HLA-DOA
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 350
- label filter
- ALEXA FLUOR 350
- technique filter
- Antibody
- dna
- TechniqueAntibody, dna, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:LRG_162
Gene info
Locus Specific Databases:IMGT/HLA Database