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DAXX (Ser495) Antibody, ALEXA FLUOR 488

  • Catalog number
    bs-5291R-A488
  • Product name
    DAXX (Ser495) Antibody, ALEXA FLUOR 488
  • Size
    100ul
  • Short name
    Anti-DAXX Ser495
  • Long name
    DAXX (Ser495) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
  • Also known as
    Anti-DAXX Ser495 PAb ALEXA FLUOR 488
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 488
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    DAXX Ser495
  • Specificity
    This is a highly specific antibody against DAXX Ser495.
  • Modification
    Phosphorylation
  • Modification Site
    Ser495
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    470-520/740
  • Subcellular location
    Cytoplasm, Nucleus
  • Source
    KLH conjugated synthetic phosphopeptide derived from human DAXX around the phosphorylation site of Ser495
  • Gene ID Number
    1616
  • Swiss Prot
    Q9UER7
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    499nm/519nm
  • Synonyms
    DAP6; EAP1; BING2; Death domain-associated protein 6; Daxx; hDaxx; ETS1-associated protein 1; Fas death domain-associated protein
  • Alternative to gene target
    • [ "death-domain associated protein", "BING2 and DAP6 and EAP1", "DAXX and IDBG-82726 and ENSG00000204209 and 102723452,1616", "androgen receptor binding", "nuclei", "Daxx and IDBG-168138 and ENSMUSG00000002307 and 13163", "DAXX and IDBG-629026 and ENSBTAG00000016830 and 504336" ]
  • Gene target
    DAXX Ser495
    • Gene info
  • Gene symbol
    DAXX
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 488
  • label filter
    • ALEXA FLUOR 488
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies