- Catalog numberbs-13752R-A488
- Product nameClaudin 16 Antibody, ALEXA FLUOR 488
- Size100ul
- PriceAsk For Price
- Short nameAnti-Claudin 16
- Long nameClaudin 16 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
- Also known asAnti-Claudin 16 PAb ALEXA FLUOR 488
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 488
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenClaudin 16
- SpecificityThis is a highly specific antibody against Claudin 16.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range90-140/305
- Subcellular locationExtracellular
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Claudin 16
- Gene ID Number10686
- Swiss ProtQ9Y5I7
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenPlays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission499nm/519nm
- SynonymsHOMG3; PCLN1; Claudin-16; Paracellin-1; PCLN-1; CLDN16
- Gene targetClaudin 16
- Identity:HGNC:14158
- Gene:TMEM204
- Long gene name:transmembrane protein 204
- Synonyms gene name:chromosome 16 open reading frame 30
- Synonyms:FLJ20898CLP24
- Discovery year:2000-12-21
- Entrez gene record:79652
- Pubmed identification:15206924
- RefSeq identity:NM_024600
- VEGA ID:OTTHUMG00000176585
- Gene symbolCLDN16, TMEM204
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 488
- label filter
- ALEXA FLUOR 488
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies