- Catalog numberbs-7649R-A594
- Product nameCIDE A Antibody, ALEXA FLUOR 594
- Size100ul
- PriceAsk For Price
- Short nameAnti-CIDE A
- Long nameCIDE A Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
- Also known asAnti-CIDE A PAb ALEXA FLUOR 594
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 594
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenCIDE A
- SpecificityThis is a highly specific antibody against CIDE A.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CIDE A
- Gene ID Number1149
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenApoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICARD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B (for cell death inducing DFF like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE A is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE A is expressed in many tissues.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission590nm/617nm
- SynonymsCell death activator CIDE A; Cell Death Inducing DFFA Like Effector A; cell death inducing DNA fragmentation factor, alpha subunit like effector A; CIDEA; CIDEA_HUMAN.
- Gene targetCIDE A
- Identity:HGNC:1976
- Gene:CIDEA
- Long gene name:cell death inducing DFFA like effector a
- Synonyms gene name:cell death-inducing DFFA-like effector a
- Synonyms:CIDE-A
- Discovery year:1998-07-15
- Entrez gene record:1149
- Pubmed identification:9564035, 18509062
- RefSeq identity:NM_001279
- VEGA ID:OTTHUMG00000131691
- Identity:HGNC:24229
- Gene:CIDEC
- Long gene name:cell death inducing DFFA like effector c
- Synonyms gene name:cell death-inducing DFFA-like effector c
- Synonyms:CIDE-3FLJ20871Fsp27
- Discovery year:2004-07-26
- Entrez gene record:63924
- Pubmed identification:12429024
- RefSeq identity:NM_022094
- VEGA ID:OTTHUMG00000128522
- Gene symbolCIDEA, CIDEC
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 594
- label filter
- ALEXA FLUOR 594
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies