- Catalog numberbs-2211R-A594
- Product nameCD80 Antibody, ALEXA FLUOR 594
- Size100ul
- PriceAsk For Price
- Short nameAnti-CD80
- Long nameCD80 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
- Also known asAnti-CD80 PAb ALEXA FLUOR 594
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 594
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenCD80
- SpecificityThis is a highly specific antibody against CD80.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range270-321/321
- Subcellular locationCytoplasm
- SourceKLH conjugated synthetic peptide derived from rat CD80
- Gene ID Number25408
- Swiss ProtG3V671
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityMouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenCD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission590nm/617nm
- SynonymsB7-1; Activation B7 1 antigen; Activation B71 antigen; B lymphocyte activation antigen B7; B7; BB1; CD 80; CD28 antigen ligand 1 B7 1 antigen; CD28 antigen ligand 1 B71 antigen; CD28LG; CD28LG1; CD80 antigen; CD80 antigen precursor;CD80 molecule; Costimulatory factor CD80; CTLA 4 counter receptor B7.1; CTLA-4 counter-receptor B7.1; LAB 7; LAB7; T lymphocyte activation antigen CD80; CD80_MOUSE.
- Alternative to gene target
- [ "CD80 molecule", "B7 and B7-1 and B7.1 and BB1 and CD28LG and CD28LG1 and LAB7", "CD80 and IDBG-51287 and ENSG00000121594 and 941", "coreceptor activity", "Cell surfaces", "Cd80 and IDBG-160288 and ENSMUSG00000075122 and 12519", "BT.27986 and IDBG-632750 and ENSBTAG00000018059 and 407131" ]
- Gene targetCD80
- Identity:HGNC:1700
- Gene:CD80
- Long gene name:CD80 molecule
- Synonyms gene name:CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), CD80 molecule
- Synonyms:B7.1, B7-1
- Discovery year:1993-12-14
- Entrez gene record:941
- Pubmed identification:1370389
- RefSeq identity:NM_005191
- Classification:B7 family, CD molecules, C2-set domain containing, V-set domain containing
- VEGA ID:OTTHUMG00000159419
- Gene symbolCD80
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 594
- label filter
- ALEXA FLUOR 594
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies