- Catalog numberbs-7735R-A647
- Product nameAMSH Antibody, ALEXA FLUOR 647
- Size100ul
- PriceAsk For Price
- Short nameAnti-AMSH
- Long nameAMSH Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
- Also known asAnti-AMSH PAb ALEXA FLUOR 647
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 647
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenAMSH
- SpecificityThis is a highly specific antibody against AMSH.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AMSH
- Gene ID Number10617
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenZinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission650nm/665nm
- SynonymsAssociated molecule with the SH3 domain of STAM; Endosome associated ubiquitin isopeptidase; Endosome-associated ubiquitin isopeptidase; STABP_HUMAN; STAM binding protein; STAM-binding protein; STAMBP.
- Gene targetAMSH
- Identity:HGNC:16950
- Gene:STAMBP
- Long gene name:STAM binding protein
- Synonyms:AMSH
- Discovery year:2004-02-04
- Entrez gene record:10617
- Pubmed identification:10383417
- RefSeq identity:NM_006463
- Classification:JAMM/MPN+ metallopeptidase family
- VEGA ID:OTTHUMG00000129817
- Identity:HGNC:24105
- Gene:STAMBPL1
- Long gene name:STAM binding protein like 1
- Synonyms gene name:STAM binding protein-like 1
- Synonyms:AMSH-LPKIAA1373AMSH-FPFLJ31524ALMalphabA399O19.2
- Discovery year:2005-10-25
- Entrez gene record:57559
- Pubmed identification:12810066, 12943674
- RefSeq identity:NM_020799
- Classification:JAMM/MPN+ metallopeptidase family
- VEGA ID:OTTHUMG00000018702
- Gene symbolSTAMBP, STAMBPL1
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 647
- label filter
- ALEXA FLUOR 647
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies