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Amisyn Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-11039R-A555
  • Product name
    Amisyn Antibody, ALEXA FLUOR 555
  • Size
    100ul
  • Short name
    Anti-Amisyn
  • Long name
    Amisyn Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-Amisyn PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Amisyn
  • Specificity
    This is a highly specific antibody against Amisyn.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Amisyn
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Amisyn is a mostly cytosolic protein related to Tomosyn which plays an important role in SNARE complex assembly. Amisyn contains a v-SNARE coiled coil homology domain that binds to Syntaxin 1A and weakly to Syntaxin 4. Three isoforms exist for Amisyn. Isoform 1 is the full length protein, isoform 2 has a different amino acid sequence between residues 204-210 and isoform 3 is missing amino acids 1-102 and contains a different sequence for amino acids 103-150. Amisyn lacks a transmembrane domain and therefore is unable to assemble into a functional, membrane-anchored SNARE complex. This suggests that Amisyn may instead be acting to maintain SNARE conformation and facilitate the binding of VAMP-2. Amisyn can inhibit exocytosis independent of Syntaxin binding.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    Amisyn; HSPC156; STXB6_HUMAN; STXBP6; Syntaxin binding protein 6; Syntaxin-binding protein 6.
  • Gene target
    Amisyn
    • Gene info
  • Gene symbol
    STXBP6
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 555
  • label filter
    • ALEXA FLUOR 555
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies