- Catalog numberGENTObs-20152R-Cy7
- Product nameAnti-DNCLI1 (Polyclonal), Cy7
- Size100 microliters
- PriceAsk For Price
- Short nameAnti-DNCLI1 Cy7
- TypeConjugated Primary Antibody
- Conjugated withCy7
- Host organismRabbit (Oryctolagus cuniculus)
- Target Protein PeptideDNCLI1
- SpecificityThis antibody reacts specifically with DNCLI1 Cy7
- ModificationNo modification has been applied to this antibody
- Modification siteNone
- ClonalityPolyclonal Antibody
- ClonePolyclonal Antibodies
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Subcellular locationsCytoplasm
- Antigen SourceKLH conjugated synthetic peptide derived from human DNCLI1
- Gene ID51143
- Swiss ProtQ9Y6G9
- ApplicationsIF(IHC-P)
- Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
- Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
- Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
- Background informationActs as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
- Purification methodPurified by Protein A.
- StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Excitation emission743nm/767nm
- SynonymsLIC1; DNCLI1; Cytoplasmic dynein 1 light intermediate chain 1; Dynein light chain A; DLC-A; Dynein light intermediate chain 1, cytosolic; DYNC1LI1
- Also known asDNCLI1 Polyclonal Antibody Cy7
- Other nameAnti-DNCLI1 Polyclonal Cy7
- AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
- Gene targetDNCLI1
- Identity:HGNC:18745
- Gene:DYNC1LI1
- Long gene name:dynein cytoplasmic 1 light intermediate chain 1
- Synonyms gene name:dynein, cytoplasmic, light intermediate polypeptide 1
- Discovery year:2002-06-12
- Entrez gene record:51143
- Pubmed identification:16260502
- RefSeq identity:NM_016141
- Classification:Dynein 1 complex subunits
- VEGA ID:OTTHUMG00000130750
- Gene symbolDYNC1LI1
- isotype filter
- Immunoglobulin G IgG
- LabelCy7
- label filter
- Cy7
- technique filter
- Polyclonal
- anti-
- anti
- TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
- Alternative techniquepolyclonals, antibodies