- Catalog numberGENTObs-2514R-A594
- Product nameAnti-CCR5/CD195 (Polyclonal), ALEXA Fluor 594
- Size100 microliters
- PriceAsk For Price
- Short nameAnti-CCR5/CD195
- TypeConjugated Primary Antibody
- Conjugated withALEXA FLUOR® 594
- Host organismRabbit (Oryctolagus cuniculus)
- Target Protein PeptideCCR5/CD195
- SpecificityThis antibody reacts specifically with CCR5/CD195
- ModificationNo modification has been applied to this antibody
- Modification siteNone
- ClonalityPolyclonal Antibody
- ClonePolyclonal Antibodies
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Subcellular locationsCytoplasm, Helical
- Antigen SourceKLH conjugated synthetic peptide derived from human CCR-5
- Gene ID1234
- Swiss ProtP51681
- ApplicationsIF(IHC-P)
- Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
- Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
- Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
- Background informationReceptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
- Purification methodPurified by Protein A.
- StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Excitation emission590nm/617nm
- SynonymsCKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5; C-C chemokine receptor type 5; C-C CKR-5; CCR5; CHEMR13; HIV-1 fusion coreceptor
- Also known asCCR5/CD195 Polyclonal Antibody
- Other nameAnti-CCR5/CD195 Polyclonal
- AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
- Alternative to gene target
- [ "chemokine (C-C motif) receptor 5 (gene/pseudogene)", "CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22", "CCR5 and IDBG-30229 and ENSG00000160791 and 1234", "chemokine (C-C motif) ligand 5 binding", "Cell surfaces", "CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017" ]
- Gene targetCCR5/CD195
- Identity:HGNC:1606
- Gene:CCR5
- Long gene name:C-C motif chemokine receptor 5
- Synonyms gene name:chemokine (C-C motif) receptor 5, chemokine (C-C motif) receptor 5 (gene/pseudogene), C-C motif chemokine receptor 5 (gene/pseudogene)
- Synonyms:CKR-5, CC-CKR-5, CKR5CD195IDDM22
- Discovery year:1996-05-15
- Entrez gene record:1234
- Pubmed identification:8639485, 9284370, 20210993
- RefSeq identity:NM_000579
- Classification:C-C motif chemokine receptors, CD molecules
- VEGA ID:OTTHUMG00000133481
- Gene symbolCCR5
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 594
- label filter
- ALEXA FLUOR 594
- technique filter
- Polyclonal
- anti-
- anti
- TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
- Alternative techniquepolyclonals, antibodies