- Catalog numberGENTObs-3010R-A594
- Product nameAnti-Bax (Ser184) (Polyclonal), ALEXA Fluor 594
- Size100 microliters
- PriceAsk For Price
- Short nameAnti-Bax (Ser184)
- TypeConjugated Primary Antibody
- Conjugated withALEXA FLUOR® 594
- Host organismRabbit (Oryctolagus cuniculus)
- Target Protein PeptideBax Ser184
- SpecificityThis antibody reacts specifically with Bax (Ser184)
- ModificationPhosphorylation
- Modification siteSer184
- ClonalityPolyclonal Antibody
- ClonePolyclonal Antibodies
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Subcellular locationsHelical
- Antigen SourceKLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184
- Gene ID581
- Swiss ProtQ07812
- ApplicationsIF(IHC-P)
- Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
- Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
- Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
- Background informationAccelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
- Purification methodPurified by Protein A.
- StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Excitation emission590nm/617nm
- SynonymsBCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX
- Also known asBax (Ser184) Polyclonal Antibody
- Other nameAnti-Bax (Ser184) Polyclonal
- AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
- Alternative to gene target
- [ "BCL2-associated X protein", "BCL2L4", "BAX and IDBG-61459 and ENSG00000087088 and 581", "BH3 domain binding", "nuclei", "Bax and IDBG-183241 and ENSMUSG00000003873 and 12028", "BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730" ]
- Gene targetBax Ser184
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 594
- label filter
- ALEXA FLUOR 594
- technique filter
- Polyclonal
- anti-
- anti
- TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
- Alternative techniquepolyclonals, antibodies