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Mouse Monoclonal IgG Anti-AGE-4 Methylglyoxal modifiied [14B5]

  • Catalog number
    AGE4-010
  • Product name
    Mouse Monoclonal IgG Anti-AGE-4 Methylglyoxal modifiied [14B5]
  • Size
    10 µg
  • Availability
    Please contact us to check the availability
  • Immunogen
    Methylglyoxal-modified BSA
  • Specificity
    AGE-4 (Methylglyoxal-modified proteins); in Western Blot no cross-reaction with glucose-modified AGEs (AGE-1), AGE-2 (Glycerolaldehyde-modified), AGE-3 (Glycolaldehyde-modified), AGE-5 (Glyoxal-modified), AGE-6 (3-DG-modified), CEL-BSA, CML-BSA and BSA
  • Species reactivity
    not relevant
  • Product presentation
    Protein G affinity purified monoclonal antibody in PBS with 2% Block Ace as stabilizer and 0.1% Proclin as preservative
  • Product category
    Primary Antibody
  • Short name
    AGE
  • Antibody s raised in
    Mouse
  • Antibody s isotype
    IgG
  • Antibody s clone
    14B5
  • Product is supplied as
    liquid concentrate
  • Recommended concentration for use
    0,1 µg/ml (WB) and 0,05 µg/ml (ELISA)
  • Protein concentration
    0.25 mg/ml
  • Positive control
    human lens, arteriosclerotic plaques
  • Tested applications
    ELISA, WB
  • Recommended secondary reagent
    As secondary system in ELISA and Western Blot we recommend biotinylated anti-mouse IgG antibody (Art. No. ZU102) in combination with streptavidin-HRPO conjugate (Art. No. ZU054) or streptavidin-alkaline phosphatase (Art. No. ZU051).
  • Storage method
    Store at -20°C
  • UniProt number
    Go to UniProt/SwissProt
  • Litterature
    1. Takeuchi M. , Makita Z., Bucala R., Suzuki T., Koike T., and Kameda Y. (2000) Immunological evidence that non-carboxymethyllysine Advanced Glycation End-products are produced from short chain sugars and dicarbonyl compounds in vivo. Mol. Med. 6; 114-125. 2. Takeuchi M., Yanase Y., Matsuura N., Yamagishi S., Kameda Y., Bucala R., and Z. Matika (2001) Immunological detection of a novel Advanced Glycation End-Product. Mol. Med. 7; 783-791. 3. Van Herreweghe F. et al. (2002) Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE.: Proc .Natl. Acad. Sci. U S A.;99(2):949-954. 4. Speer O. et al.(2003) Rapid suppression of mitochondrial permeability transition by methylglyoxal. Role of reversible arginine modification. J. Biol .Chem. 278(37):34757-63.
  • Tips
    *Gentaur antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
  • Other products
    Other_products
  • Gene target
    Monoclonal AGE-4 Methylglyoxal modifiied [14B5]
    • Gene info
    Gene info
    • Identity:HGNC:37522
    • Gene:PIRC18
    • Long gene name:piwi-interacting RNA cluster 18
    • Discovery year:2009-11-05
    • Entrez gene record:100313906
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
    Gene info
    • Identity:HGNC:37520
    • Gene:PIRC16
    • Long gene name:piwi-interacting RNA cluster 16
    • Discovery year:2009-11-05
    • Entrez gene record:100313849
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
    Gene info
    Gene info
    Gene info
    Gene info
    Gene info
    • Identity:HGNC:37521
    • Gene:PIRC17
    • Long gene name:piwi-interacting RNA cluster 17
    • Discovery year:2009-11-05
    • Entrez gene record:100313809
    • Pubmed identification:17881367
    • Classification:Piwi-interacting RNA clusters
  • Gene symbol
    MIR1302-4, PIRC18, PIRC16, SNORD114-4, MIR941-4, IGKV2OR2-4, ANKRD20A12P, PIRC17
  • Host
    mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG, IgG
  • isotype filter
    • IgG
  • technique filter
    • Mouse monoclonal
    • anti-
    • Mouse
    • anti
    • IgG
  • Technique
    Mouse monoclonal, anti-, Mouse, anti, IgG, antibody to, antibodies, IgGs, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Alternative technique
    murine, antibodies, immunoglobulins